DRAGdb: Drug Resistance Associated Genes
Number of mutation entries of inhA in Mycobacterium tuberculosis is 30
PROVEAN score threshold is -2.5. Variants with score = or < -2.5 are considered deleterious.Variants with score > -2.5 are considered neutral.
| ORGANISM_NAME | GENE_NAME | ENSEMBL_ID | DRUG_NAME | NUCLEOTIDE_POSITION | NUCLEOTIDE_MUTATION | AMINOACID_POSITION | AMINOACID_MUTATION | PROVEAN_SCORE | SAMPLE_LOCATION |
|---|---|---|---|---|---|---|---|---|---|
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | -15 | C - T | NA | NA | NA | Spain |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | -8 | T - C | NA | NA | NA | Spain |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | -8 | T - A | NA | NA | NA | Spain |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | -15 | C - T | NA | NA | NA | Morocco |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | -8 | T - C | NA | NA | NA | Morocco |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | -8 | T - A | NA | NA | NA | Morocco |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | 283 -284 | ATT - CCT | 95 | Ile - Pro | -6.932 | Germany and Nepal |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | 24 | AAA - AAC | 8 | Lys - Asn | -4.872 | South Korea |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | 62 | ATC - ACC | 21 | Ile - Thr | -4.762 | United States |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | 581 | ATC - ACC | 194 | Ile - Thr | -3.813 | Hong Kong in China |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | 233 | GTG - GCG | 78 | Val - Ala | -3.509 | United States |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | 47 | ATC - ACC | 16 | Ile - Thr | -3.21 | United States |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | 280 | TCG - GCG | 94 | Ser - Ala | -1.909 | South Korea |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | 61 | ATC - GTC | 21 | Ile - Val | -0.96 | United States |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | 140 | ATT - ACT | 47 | Ile - Thr | 1.137 | United States |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | NA | NA | 202 | Arg - Gly | NA | Taiwan |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | NA | NA | 217 | Glu - Asp | NA | Taiwan |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | -15 | C - T | NA | NA | NA | China |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | -8 | T - C | NA | NA | NA | China |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | -34 | C - Deletion | NA | NA | NA | China |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | -8 | T - A | NA | NA | NA | China |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | -17 | G - T | NA | NA | NA | China |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | -34 | C - T | NA | NA | NA | China |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | 281 | TCG - TTG | 94 | Ser - Leu | -5.272 | NA |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | 284 | ATT - ACT | 95 | Ile - Thr | -4.932 | NA |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | -15 | C - T | NA | NA | NA | Moldova and India and South Africa |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | -17 | G - T | NA | NA | NA | Moldova and India and South Africa |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | -8 | T - C | NA | NA | NA | Moldova and India and South Africa |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | -8 | T - G | NA | NA | NA | Moldova and India and South Africa |
| Mycobacterium tuberculosis | inhA | Rv1484 | Isoniazid | -8 | T - A | NA | NA | NA | Moldova and India and South Africa |