DRAG

DRAGdb: Drug Resistance Associated Genes

Number of mutation entries of rpsL in Mycobacterium tuberculosis is 113

PROVEAN score threshold is -2.5. Variants with score = or < -2.5 are considered deleterious.Variants with score > -2.5 are considered neutral.

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ORGANISM_NAME	GENE_NAME	ENSEMBL_ID	DRUG_NAME	NUCLEOTIDE_POSITION	NUCLEOTIDE_MUTATION	AMINOACID_POSITION	AMINOACID_MUTATION	PROVEAN_SCORE	SAMPLE_LOCATION
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	257	G - C	86	Arg - Pro	-6.833	NA
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - ATG	88	Lys - Met	-5.647	Chengdu in China
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - ATG	88	Lys - Met	-5.647	Iran
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - ATG	88	Lys - Met	-5.647	Iran
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - ATG	88	Lys - Met	-5.647	Japan
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - ATG	88	Lys - Met	-5.647	NA
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - ACG	88	Lys - Thr	-5.643	Kaohsiung in Taiwan
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - ACG	88	Lys - Thr	-5.643	Barcelona in Spain
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - ACG	88	Lys - Thr	-5.643	Japan
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - ACG	88	Lys - Thr	-5.643	NA
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - ACG	88	Lys - Thr	-5.643	NA
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	211	GGC�-�AGC	71	Gly�-�Ser	-5.576	China
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - ACG	43	Lys - Thr	-5.512	Beijing in China
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - ACG	43	Lys - Thr	-5.512	NA
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	332	AAA - ATA	111	Lys - Ile	-4.826	Khyber Pakhtunkhwa in Pakistan
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	129	AAG - AAC	43	Lys - Asn	-4.582	Beijing in China
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	26	CGC - CAC	9	Arg - His	-4.225	Hong Kong
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	104	C - A	35	Thr - Asn	-4.076	NA
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	262	AAG - CAG	88	Lys - Gln	-3.688	Barcelona in Spain
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	262	AAG - CAG	88	Lys - Gln	-3.688	Chiang Rai Province in Thailand
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	262	AAG - CAG	88	Lys - Gln	-3.688	Japan
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	262	AAG - CAG	88	Lys - Gln	-3.688	Madang in Papua New Guinea
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	262	AAG - CAG	88	Lys - Gln	-3.688	NA
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	262	AAG - CAG	88	Lys - Gln	-3.688	NA
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	262	AAG - CAG	88	Lys - Gln	-3.688	NA
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	262	AAG - CAG	88	Lys - Gln	-3.688	Poland
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	262	AAG - CAG	88	Lys - Gln	-3.688	Shenzhen of China
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	262	AAG - CAG	88	Lys - Gln	-3.688	southeast Mexico
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	127	A - C	43	Lys - Gln	-3.656	Chengdu in China
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	76	G - T	26	Gly - Cys	-3.065	Chengdu in China
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	277	GTG - ATG	93	Val - Met	-2.898	Vietnam
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	131	AAG - AGG	44	Lys - Arg	-2.795	Iran
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	119	C - T	40	Thr - Ile	-2.68	Poland
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	NA
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Iran
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin / Kanamycin / Amikacin	128	AAG - AGG	43	Lys - Arg	-2.663	Latvia
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Kaohsiung in Taiwan
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Pakistan
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Barcelona in Spain
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Beijing in China
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Beijing in China
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Cairo in Egypt
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Central Region of Cameroon
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Chengdu in China
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Chiang Rai Province in Thailand
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys�-�Arg	-2.663	China
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Chongqing in China
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	D�zce in Turkey
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Guangdong in China
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Hong Kong
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Iran
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Japan
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Japan
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Khyber Pakhtunkhwa in Pakistan
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Madang in Papua New Guinea
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Monterrey in Mexico
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	NA
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	NA
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	NA
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	NA
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	North India
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Poland
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Poland
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Republic of Korea
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Shenzhen of China
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Siberia
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Siberia
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Sierra Leone
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	south of Brazil
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	southeast Mexico
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Tbilisi in Republic of Georgia
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Tianjin in China
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Uganda
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Vietnam
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Chennai in India
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	NA
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	NA
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	NA
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	Iran
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	Kaohsiung in Taiwan
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	Pakistan
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	NA
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg�	-2.508	Barcelona in Spain
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	262	AAG - AGG	88	Lys - Arg	-2.508	Beijing in China
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	Cairo in Egypt
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	Chengdu in China
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys�-�Arg	-2.508	China
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	Guangdong in China
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	Japan
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	Khyber Pakhtunkhwa in Pakistan
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	Madang in Papua New Guinea
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	NA
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	NA
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	NA
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	NA
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	North India
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	Poland
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	Poland
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	Republic of Korea
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	Siberia
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	Sierra Leone
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	south of Brazil
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	southeast Mexico
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	Tianjin in China
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	Uganda
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	117	C - T	39	Thr - Thr	0	Chengdu in China
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	117	ACC - ACT	39	Thr - Thr	0	China
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	117	C - T	39	Thr - Thr	0	Poland
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	294	ATC - ATT	98	Ile - Ile	0	Poland
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	363	AAA - AAG	121	Lys - Lys	0	Iran
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	363	AAA - AAG	121	Lys - Lys	0	New Delhi and Chandigarh in India
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	128	AAG - AGG	43	Lys - Arg	-2.663	Yunnan in China
Mycobacterium tuberculosis	rpsL	Rv0682	Streptomycin	263	AAG - AGG	88	Lys - Arg	-2.508	Yunnan in China

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