DRAGdb: Drug Resistance Associated Genes
Number of mutation entries in Brucella species is 10
PROVEAN score threshold is -2.5. Variants with score = or < -2.5 are considered deleterious.Variants with score > -2.5 are considered neutral.
| ORGANISM_NAME | GENE_NAME | ENSEMBL_ID | DRUG_NAME | NUCLEOTIDE_POSITION | NUCLEOTIDE_MUTATION | AMINOACID_POSITION | AMINOACID_MUTATION | PROVEAN_SCORE | SAMPLE_LOCATION |
|---|---|---|---|---|---|---|---|---|---|
| Brucella abortus | rpoB | DK54_1403 | Rifampicin | 1576 | GAC - TAC | 526 | Asp - Tyr | -8.53 | NA |
| Brucella melitensis | rpoB | BV91_13615 | Rifampicin | 458 | GTT - TTT | 154 | Val - Phe | -4.774 | NA |
| Brucella melitensis | rpoB | BV91_13615 | Rifampicin | 466 | GAC - TAC | 156 | Asp - Tyr | NA | NA |
| Brucella melitensis | rpoB | BV91_13615 | Rifampicin | 1576 | GAC - AAC | 526 | Asp - Asn | -4.724 | NA |
| Brucella melitensis | rpoB | BV91_13615 | Rifampicin | 1577 | GAC - GGC | 526 | Asp - Gly | -6.646 | NA |
| Brucella melitensis | rpoB | BV91_13615 | Rifampicin | 1606 | CAC - TAC | 536 | His - Tyr | -5.786 | NA |
| Brucella melitensis | rpoB | BV91_13615 | Rifampicin | 1607 | CAC - CTC | 536 | His - Leu | -10.609 | NA |
| Brucella melitensis | rpoB | BV91_13615 | Rifampicin | 1615 | CGC - AGC | 539 | Arg - Ser | -5.802 | NA |
| Brucella melitensis | rpoB | BV91_13615 | Rifampicin | 1622 | TCG - TTG | 541 | Ser - Leu | -5.798 | NA |
| Brucella melitensis | rpoB | BV91_13615 | Rifampicin | 1721 | CCG - CTG | 574 | Pro - Leu | -9.39 | NA |