DRAGdb: Drug Resistance Associated Genes
Number of mutation entries in Campylobacter species is 99
PROVEAN score threshold is -2.5. Variants with score = or < -2.5 are considered deleterious.Variants with score > -2.5 are considered neutral.
| ORGANISM_NAME | GENE_NAME | ENSEMBL_ID | DRUG_NAME | NUCLEOTIDE_POSITION | NUCLEOTIDE_MUTATION | AMINOACID_POSITION | AMINOACID_MUTATION | PROVEAN_SCORE | SAMPLE_LOCATION |
|---|---|---|---|---|---|---|---|---|---|
| Campylobacter coli | gyrA | VC76_04995 | Fluoroquinolone (Enrofloxacin) | 257 | ACT - ATT | 86 | Thr - Ile | -3.687 | Thailand |
| Campylobacter coli | gyrA | VC76_04995 | Fluoroquinolone | 257 | ACT - ATT | 86 | Thr - Ile | -3.687 | United States |
| Campylobacter coli | gyrA | VC76_04995 | Fluoroquinolone | 257 | ACT - ATT | 86 | Thr - Ile | -3.687 | NA |
| Campylobacter coli | gyrB | VC76_00015 | Fluoroquinolone (Ciprofloxacin) | 1471 | ATG - CTG | 491 | Met - Leu | -2.397 | Switzerland |
| Campylobacter coli | rpsL | VC76_02580 | Streptomycin | 128 | AAG - AGG | 43 | Lys - Arg | -2.628 | NA |
| Campylobacter coli | rpsL | VC76_02580 | Streptomycin | 263 | AAG - AGG | 88 | Lys - Arg | -2.703 | NA |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 310 | C - T | 104 | Pro - Ser | -3.377 | NA |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 330 | GGC - GGT | 110 | Gly - Gly | 0 | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 351 | GTG - GTC | 117 | Val - Val | NA | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 354 | ATA - ATC | 118 | Ile - Ile | NA | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 357 | AGT - AGC | 119 | Ser - Ser | 0 | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 360 | GCC - GCT | 120 | Ala - Ala | 0 | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 364 | GCG - TCG | 122 | Ala - Ser | -2.89 | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 408 | GAG - GAT | 136 | Glu - Asp | -2.718 | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 411 | AGC - AGT | 137 | Ser - Ser | NA | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 435 | AGC - AGT | 145 | Ser - Ser | NA | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 445 | GTT - ATT | 149 | Val - Ile | -0.305 | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 447 | TTC - TTT | 149 | Phe - Phe | NA | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 456 | TAT - TAC | 152 | Tyr - Tyr | 0 | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 471 | AGC - AGT | 157 | Ser - Ser | 0 | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 483 | GTT - GTC | 161 | Val - Val | 0 | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Enrofloxacin) | 608 | AAT - AGT | 203 | Asn - Ser | -3.919 | Thailand |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone | 608 | AAT - AGT | 203 | Asn - Ser | -3.919 | United States |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Enrofloxacin) | 617 | GCA - GTA | 206 | Ala - Val | 0.83 | Thailand |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 63 | AAA - AAG | 21 | Lys - Lys | 0 | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Enrofloxacin) | 64 | AGT - GGT | 22 | Ser - Gly | -2.009 | Thailand |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone | 64 | AGT - GGT | 22 | Ser - Gly | -2.009 | United States |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 64 | AGT - GGT | 22 | Ser - Gly | -2.009 | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 72 | TAT - TAC | 24 | Tyr - Tyr | 0 | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 84 | TCT - TCC | 28 | Ser - Ser | 0 | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone | 854 | G - A | 285 | Arg - Lys | NA | United States |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 115 | GCA - TCA | 39 | Ala - Ser | NA | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 117 | GAC - GAT | 39 | Asp - Asp | 0 | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 146 | AGA - AAA | 48 | Arg - Lys | NA | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 177 | GAG - GAA | 59 | Glu - Glu | 0 | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 189 | GAA - GAG | 63 | Glu - Glu | NA | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 207 | CAG - CAA | 69 | Gln - Gln | NA | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 231-232 | GGT - GCC | 78 | Gly - Gly | 0 | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 243 | CAC - CAT | 81 | His - His | 0 | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 253 | ACA - GCA | 85 | Thr - Ala | NA | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Enrofloxacin) | 257 | ACA - ATA | 86 | Thr - Ile | -3.321 | Thailand |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone | 257 | ACA - ATA | 86 | Thr - Ile | -3.321 | China |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone | 257 | ACA - ATA | 86 | Thr - Ile | -3.321 | United States |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone | 257 | ACA - ATA | 86 | Thr - Ile | -3.321 | NA |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Nalidixic Acid | 256 | A - G | 86 | Thr - Ala | -1.944 | Lima in Peru |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 257 | ACA - ATA | 86 | Thr - Ile | -3.321 | Lima in Peru |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 257 | ACA - ATA | 86 | Thr - Ile | -3.321 | Lithuania |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 257 | ACA - ATA | 86 | Thr - Ile | -3.321 | NA |
| Campylobacter jejuni | gyrA | CJJ5050_08730 | Fluoroquinolone (Ciprofloxacin) | 291 | AAG - AAA | 97 | Lys - Lys | NA | Lithuania |
| Campylobacter jejuni | gyrB | CJJ5050_15010 | Fluoroquinolone (Ciprofloxacin) | 1296 | AGA - AGG | 432 | Arg - Arg | 0 | Beijing in China |
| Campylobacter jejuni | gyrB | CJJ5050_15010 | Fluoroquinolone (Ciprofloxacin) | 1308 | TTC - TTT | 436 | Phe - Phe | 0 | Beijing in China |
| Campylobacter jejuni | gyrB | CJJ5050_15010 | Fluoroquinolone (Ciprofloxacin) | 1359 | CTA - TTA | 454 | Leu - Leu | 0 | Beijing in China |
| Campylobacter jejuni | gyrB | CJJ5050_15010 | Fluoroquinolone (Ciprofloxacin) | 1413 | GGC - GGT | 471 | Gly - Gly | 0 | Beijing in China |
| Campylobacter jejuni | gyrB | CJJ5050_15010 | Fluoroquinolone (Ciprofloxacin) | 1449 | CTT - CTC | 483 | Leu - Leu | 0 | Beijing in China |
| Campylobacter jejuni | gyrB | CJJ5050_15010 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 469 | T - C | NA | NA | NA | Senegal |
| Campylobacter jejuni | gyrB | CJJ5050_15010 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 389 | C - T | NA | NA | NA | Senegal |
| Campylobacter jejuni | gyrB | CJJ5050_15010 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 403 | A - G | NA | NA | NA | Senegal |
| Campylobacter jejuni | gyrB | CJJ5050_15010 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 436 | C - T | NA | NA | NA | Senegal |
| Campylobacter jejuni | gyrB | CJJ5050_15010 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 454 | C - T | NA | NA | NA | Senegal |
| Campylobacter sps. | gyrA | NA | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 257 | C - T | 86 | Thr - Ile | NA | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 298 - 300 | NA | 100 | Ile - Val | 0.178 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 322 - 324 | NA | 108 | Thr - His | -1.111 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 31 - 33 | NA | 11 | Ile - Phe | -0.475 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 31 - 33 | NA | 11 | Ile - Thr | 0.382 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 328 - 330 | NA | 110 | Phe - Ile | 0.033 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 339 - 342 | NA | 114 | Val - Ala | -3.6 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 355 - 357 | NA | 119 | Thr - Ala | 0.17 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 358 - 360 | NA | 120 | Glu - Gln | -0.892 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 39 | A - Insertion | 13 | Leu - Stop | NA | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 395 | T - Deletion | 132 | Met - Arg | -2.783 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 397 - 399 | NA | 133 | Arg - Lys | 1.058 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 395 | T - Deletion | 134 | Ala - Gln | -1.775 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 395 | T - Deletion | 136 | Asp - Ile | -1.817 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 395 | T - Deletion | 137 | Leu - Stop | NA | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 426 | T - Deletion | 144 | Leu - Stop | NA | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 460 - 462 | NA | 154 | Tyr - Leu | -6.433 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 460 | C - Insertion | 155 | Lys - Stop | NA | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 475 - 477 | NA | 159 | Ala - Val | 2.1 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 478 - 480 | NA | 160 | Gln - Lys | -0.322 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 493 - 495 | NA | 165 | Asp - Gly | 0.553 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 502 - 504 | NA | 168 | Arg - His | -0.017 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 502 - 504 | NA | 168 | Arg - Asp | 0.927 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 547 - 549 | NA | 183 | Thr - Asn | 0.711 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 550 - 552 | NA | 184 | Phe - Ser | 0.956 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 550 - 552 | NA | 184 | Phe - Leu | 0.678 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 554 | NA | 185 | Lys - Thr | -0.922 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 559 - 561 | NA | 187 | Phe - Ser | 0.097 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 558 - 572 | TTTCACACGCAAAAT - Deletion | 187 - 191 | NA | NA | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 561 - 569 | CACACGCAA - Deletion | 188 - 190 | NA | NA | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 565 - 567 | NA | 189 | Arg - His | -0.058 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 568 | NA | 190 | Lys - Glu | 0.133 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 572 | NA | 191 | Ile - Thr | -0.183 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 571 | NA | 191 | Ile - Leu | 0.117 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 139 | G - Deletion | 47 - 49 | Glu Ile Leu - Lys Ser Stop | NA | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 16 - 18 | NA | 6 | His - Asp | 0.666 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 181 -183 | NA | 61 | Ala - Ile | 1.417 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 25 - 27 | NA | 9 | Glu - Lys | -0.594 | NA |
| Campylobacter upsaliensis | gidB / rsmG | CUP1073 | Streptomycin | 274 - 276 | NA | 92 | Ala - Ser | -1.058 | NA |
| Campylobacter upsaliensis | rpsL | CUP1684 | Streptomycin | 263 | AAA - AGA | 88 | Lys - Arg | NA | NA |