DRAGdb: Drug Resistance Associated Genes
Number of mutation entries in Enterococcus faecalis species is 15
PROVEAN score threshold is -2.5. Variants with score = or < -2.5 are considered deleterious.Variants with score > -2.5 are considered neutral.
| ORGANISM_NAME | GENE_NAME | ENSEMBL_ID | DRUG_NAME | NUCLEOTIDE_POSITION | NUCLEOTIDE_MUTATION | AMINOACID_POSITION | AMINOACID_MUTATION | PROVEAN_SCORE | SAMPLE_LOCATION |
|---|---|---|---|---|---|---|---|---|---|
| Enterococcus faecalis | gyrA | EE55_10450 | Fluoroquinolone | 247 - 249 | NA | 83 | Ser - Arg | -4.642 | Gyeonggi Province in Korea |
| Enterococcus faecalis | gyrA | EE55_10450 | Fluoroquinolone | 248 | AGC - ATC | 83 | Ser - Ile | -5.514 | Gyeonggi Province in Korea |
| Enterococcus faecalis | gyrA | EE55_10450 | Fluoroquinolone | 248 | C - T | 83 | Ser - Phe | -5.561 | Gyeonggi Province in Korea |
| Enterococcus faecalis | gyrA | EE55_10450 | Fluoroquinolone | 248 | C - A | 83 | Ser - Tyr | -5.566 | Gyeonggi Province in Korea |
| Enterococcus faecalis | gyrA | EE55_10450 | Fluoroquinolone | 260 | A - G | 87 | Glu - Gly | -5.973 | Gyeonggi Province in Korea |
| Enterococcus faecalis | rpoB | EE55_15170 | Rifampicin | 412 | G - T | 138 | Val - Phe | -4.498 | NA |
| Enterococcus faecalis | rpoB | EE55_15170 | Rifampicin | 1426 | C - A | 476 | Gln - Lys | -3.58 | NA |
| Enterococcus faecalis | rpoB | EE55_15170 | Rifampicin | 1454 | G - A | 485 | Gly - Asp | -1.996 | NA |
| Enterococcus faecalis | rpoB | EE55_15170 | Cephalosporin (Cefuroxime / Ceftriaxone And Ceftazidime) / Rifampicin | 1456 | C - T | 486 | His - Tyr | NA | NA |
| Enterococcus faecalis | rpoB | EE55_15170 | Rifampicin | 1465 | C - G | 489 | His - Asp | -7.143 | NA |
| Enterococcus faecalis | rpoB | EE55_15170 | Rifampicin | 1466 | A - G | 489 | His - Arg | -6.451 | NA |
| Enterococcus faecalis | rpoB | EE55_15170 | Rifampicin | 1466 | A - C | 489 | His - Pro | -8.244 | NA |
| Enterococcus faecalis | rpoB | EE55_15170 | Rifampicin | 1465 | C - T | 489 | His - Tyr | -5.058 | NA |
| Enterococcus faecalis | rpoB | EE55_15170 | Rifampicin | 1475 | G - A | 492 | Arg - His | -4.476 | NA |
| Enterococcus faecalis | rpoB | EE55_15170 | Rifampicin | 1481 | C - T | 494 | Ser - Leu | -5.375 | NA |