DRAGdb: Drug Resistance Associated Genes
Number of mutation entries in Haemophilus influenzae species is 15
PROVEAN score threshold is -2.5. Variants with score = or < -2.5 are considered deleterious.Variants with score > -2.5 are considered neutral.
| ORGANISM_NAME | GENE_NAME | ENSEMBL_ID | DRUG_NAME | NUCLEOTIDE_POSITION | NUCLEOTIDE_MUTATION | AMINOACID_POSITION | AMINOACID_MUTATION | PROVEAN_SCORE | SAMPLE_LOCATION |
|---|---|---|---|---|---|---|---|---|---|
| Haemophilus influenzae | gyrA | CK45_03660 | Fluoroquinolone (Tosufloxacin / Levofloxacin) | 251 | C - T | 84 | Ser - Leu | -4.057 | Tokyo in Japan |
| Haemophilus influenzae | gyrB | CK45_02875 | Quinolone | 1199 | C - T | 400 | Ala - Val | -2.564 | Japan |
| Haemophilus influenzae | gyrB | CK45_02875 | Quinolone | 1287 | NA | 429 | Asp - Glu | -2.79 | Japan |
| Haemophilus influenzae | gyrB | CK45_02875 | Quinolone | 1400 | C - A | 467 | Ser - Tyr | -4.084 | Japan |
| Haemophilus influenzae | gyrB | CK45_02875 | Novobiocin | 262 | G - T | 88 | Asp - Tyr | NA | NA |
| Haemophilus influenzae | rpoB | CK45_02345 | Rifampicin | 1538 | A - T | 513 | Gln - Leu | -6.777 | NA |
| Haemophilus influenzae | rpoB | CK45_02345 | Rifampicin | 1546 | G - A | 516 | Asp - Asn | -4.809 | NA |
| Haemophilus influenzae | rpoB | CK45_02345 | Rifampicin | 1547 | A - C | 516 | Asp - Ala | -7.705 | NA |
| Haemophilus influenzae | rpoB | CK45_02345 | Rifampicin | 1546 | G - T | 516 | Asp - Tyr | -8.682 | NA |
| Haemophilus influenzae | rpoB | CK45_02345 | Rifampicin | 1547 | A - T | 516 | Asp - Val | -8.679 | NA |
| Haemophilus influenzae | rpoB | CK45_02345 | Rifampicin | 1552 - 1554 | NA | 518 | Asn - Asp | -3.815 | NA |
| Haemophilus influenzae | rpoB | CK45_02345 | Rifampicin | 1577 | A - T | 526 | His - Leu | -10.63 | NA |
| Haemophilus influenzae | rpoB | CK45_02345 | Rifampicin | 1576 | C - A | 526 | His - Asn | -6.759 | NA |
| Haemophilus influenzae | rpoB | CK45_02345 | Rifampicin | 1576 | C - T | 526 | His - Tyr | -5.801 | NA |
| Haemophilus influenzae | rpoB | CK45_02345 | Rifampicin | 1601 | T - C | 534 | Leu - Ser | NA | NA |