DRAGdb: Drug Resistance Associated Genes
Number of mutation entries in Salmonella species is 78
PROVEAN score threshold is -2.5. Variants with score = or < -2.5 are considered deleterious.Variants with score > -2.5 are considered neutral.
| ORGANISM_NAME | GENE_NAME | ENSEMBL_ID | DRUG_NAME | NUCLEOTIDE_POSITION | NUCLEOTIDE_MUTATION | AMINOACID_POSITION | AMINOACID_MUTATION | PROVEAN_SCORE | SAMPLE_LOCATION |
|---|---|---|---|---|---|---|---|---|---|
| Salmonella enterica | gyrB | MC58_18210 | Quinolone | 1391 | C - A | 464 | Ser - Tyr | NA | NA |
| Salmonella enterica | rpoB | MC58_16645 | Rifampicin | 1535 | A - G | 512 | Gln - Arg | NA | NA |
| Salmonella enterica Serovar Dublin | gyrA | AEW76_09460 | Quinolone | 248 | C - T | 83 | Ser - Phe | -4.548 | NA |
| Salmonella enterica Serovar Dublin | gyrA | AEW76_09460 | Quinolone | 259 | G - T | 87 | Asp - Tyr | -8.274 | NA |
| Salmonella enterica Serovar Enteritidis | gyrA | CS37_11380 | Nalidixic Acid | 248 | C - T | 83 | Ser - Phe | -4.548 | Brazil |
| Salmonella enterica Serovar Enteritidis | gyrA | CS37_11380 | Fluoroquinolone (Ciprofloxacin / Norfloxacin) / Nalidixic Acid | 248 | AGC - ATC | 83 | Ser - Ile | -4.182 | Thailand |
| Salmonella enterica Serovar Enteritidis | gyrA | CS37_11380 | Fluoroquinolone (Ciprofloxacin / Norfloxacin) / Nalidixic Acid | 248 | C - T | 83 | Ser - Phe | -4.548 | Thailand |
| Salmonella enterica Serovar Enteritidis | gyrA | CS37_11380 | Fluoroquinolone (Ciprofloxacin / Norfloxacin) / Nalidixic Acid | 248 | C - T | 83 | Ser - Phe | -4.548 | Thailand |
| Salmonella enterica Serovar Enteritidis | gyrA | CS37_11380 | Fluoroquinolone (Ciprofloxacin / Norfloxacin) / Nalidixic Acid | 248 | C - A | 83 | Ser - Tyr | -4.565 | Thailand |
| Salmonella enterica Serovar Enteritidis | gyrA | CS37_11380 | Nalidixic Acid | 259 | G - A | 87 | Asp - Asn | -4.56 | Brazil |
| Salmonella enterica Serovar Enteritidis | gyrA | CS37_11380 | Nalidixic Acid | 259 | G - T | 87 | Asp - Tyr | -8.274 | Brazil |
| Salmonella enterica Serovar Enteritidis | gyrA | CS37_11380 | Fluoroquinolone (Ciprofloxacin) | 260 | A - G | 87 | Asp - Gly | -6.468 | NA |
| Salmonella enterica Serovar Enteritidis | gyrA | CS37_11380 | Fluoroquinolone (Ciprofloxacin / Norfloxacin) / Nalidixic Acid | 259 | G - A | 87 | Asp - Asn | -4.56 | Thailand |
| Salmonella enterica Serovar Enteritidis | gyrA | CS37_11380 | Fluoroquinolone (Ciprofloxacin / Norfloxacin) / Nalidixic Acid | 260 | A - G | 87 | Asp - Gly | -6.468 | Thailand |
| Salmonella enterica Serovar Enteritidis | gyrA | CS37_11380 | Fluoroquinolone (Ciprofloxacin / Norfloxacin) / Nalidixic Acid | 259 | G - T | 87 | Asp - Tyr | -8.274 | Thailand |
| Salmonella enterica Serovar Enteritidis | gyrA | CS37_11380 | Nalidixic Acid | 289 | T - C | 97 | Ser - Pro | -4.509 | Brazil |
| Salmonella enterica Serovar Enteritidis | gyrB | CS37_18835 | Fluoroquinolone | 1398 | A - T | 466 | Glu - Asp | -2.044 | Beijing in China |
| Salmonella enterica Serovar Enteritidis | gyrB | CS37_18835 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 1398 | A - T | 466 | Glu - Asp | -2.044 | NA |
| Salmonella enterica Serovar Indiana | gyrA | SEEI1959_02253 | Fluoroquinolone (Ciprofloxacin) | 248 | C - T | 83 | Ser - Phe | -4.548 | NA |
| Salmonella enterica Serovar Indiana | gyrA | SEEI1959_02253 | Fluoroquinolone (Ciprofloxacin) | 260 | A - G | 87 | Asp - Gly | -6.468 | NA |
| Salmonella enterica Serovar Infantis | gyrA | SIN_02308 | Fluoroquinolone (Ciprofloxacin) | 259 | G - T | 87 | Asp - Tyr | -8.274 | United States |
| Salmonella enterica Serovar Kentucky | gyrA | TJ54_10510 | Quinolone | 248 | C - T | 83 | Ser - Phe | NA | Ethiopia |
| Salmonella enterica Serovar Kentucky | gyrA | TJ54_10510 | Quinolone | 248 | C - A | 83 | Ser - Tyr | NA | Ethiopia |
| Salmonella enterica Serovar Kentucky | gyrA | TJ54_10510 | Quinolone | 260 | A - G | 87 | Asp - Gly | NA | Ethiopia |
| Salmonella enterica Serovar Newport | gyrB | AEV63_16010 | Quinolone | 1310 | G - T | 437 | Arg - Leu | NA | NA |
| Salmonella enterica Serovar Senftenberg | gyrB | AEU05_22595 | Quinolone | 1259 | A - G | 420 | Tyr - Cys | NA | NA |
| Salmonella enterica Serovar Typhi | gyrA | ERS326222_03263 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 248 | C - T | 83 | Ser - Phe | -4.548 | India |
| Salmonella enterica Serovar Typhi | gyrA | ERS326222_03263 | Fluoroquinolone (Ciprofloxacin) | 248 | C - T | 83 | Ser - Phe | -4.548 | Kolkata in India |
| Salmonella enterica Serovar Typhi | gyrA | ERS326222_03263 | Fluoroquinolone (Ciprofloxacin) | 248 | C - T | 83 | Ser - Phe | -4.548 | NA |
| Salmonella enterica Serovar Typhi | gyrA | ERS326222_03263 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 259 | G - A | 87 | Asp - Asn | -4.56 | India |
| Salmonella enterica Serovar Typhi | gyrA | ERS326222_03263 | Fluoroquinolone (Ciprofloxacin) | 259 | G - A | 87 | Asp - Asn | -4.56 | Kolkata in India |
| Salmonella enterica Serovar Typhi | gyrA | ERS326222_03263 | Fluoroquinolone (Ciprofloxacin) | 260 | A - G | 87 | Asp - Gly | -6.468 | Kolkata in India |
| Salmonella enterica Serovar Typhi | gyrA | ERS326222_03263 | Fluoroquinolone (Ciprofloxacin) | 259 | G - A | 87 | Asp - Asn | -4.56 | NA |
| Salmonella enterica Serovar Typhi | gyrB | ERS326222_04129 | Fluoroquinolone (Ciprofloxacin) | 1391 | C - T | 464 | Ser - Phe | -4.058 | France |
| Salmonella enterica Serovar Typhi | gyrB | ERS326222_04129 | Fluoroquinolone (Ciprofloxacin) | 1391 | C - A | 464 | Ser - Tyr | -4.064 | France |
| Salmonella enterica Serovar Typhi | gyrB | ERS326222_04129 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 1391 | C - T | 464 | Ser - Phe | -4.058 | India |
| Salmonella enterica Serovar Typhi | gyrB | ERS326222_04129 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 1389 - 1392 | NA | 464 | Ser - Thr | -2.039 | India |
| Salmonella enterica Serovar Typhi | gyrB | ERS326222_04129 | Fluoroquinolone (Ciprofloxacin) | 1391 | C - A | 464 | Ser - Tyr | -4.064 | India |
| Salmonella enterica Serovar Typhi | gyrB | ERS326222_04129 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 1391 | C - A | 464 | Ser - Tyr | -4.064 | India |
| Salmonella enterica Serovar Typhi | gyrB | ERS326222_04129 | Fluoroquinolone (Ciprofloxacin) | 1391 | C - T | 464 | Ser - Phe | -4.058 | NA |
| Salmonella enterica Serovar Typhi | gyrB | ERS326222_04129 | Fluoroquinolone (Ciprofloxacin) | 1390 - 1392 | NA | 464 | Ser - Thr | -2.039 | NA |
| Salmonella enterica Serovar Typhi | gyrB | ERS326222_04129 | Fluoroquinolone (Ciprofloxacin) | 1391 | C - A | 464 | Ser - Tyr | -4.064 | NA |
| Salmonella enterica Serovar Typhi | gyrB | ERS326222_04129 | Fluoroquinolone (Ciprofloxacin) | 1391 | TCC - TTC | 464 | Ser - Phe | -4.058 | Sub-Saharan Africa |
| Salmonella enterica Serovar Typhimurium | gyrA | CY43_12185 | Fluoroquinolone (Marbofloxacin) | 248 | C - T | 83 | Ser - Phe | -4.548 | NA |
| Salmonella enterica Serovar Typhimurium | gyrA | CY43_12185 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) / Triclosan | 248 | C - T | 83 | Ser - Phe | -4.548 | NA |
| Salmonella enterica Serovar Typhimurium | gyrA | CY43_12185 | Fluoroquinolone (Ciprofloxacin) | 248 | C - T | 83 | Ser - Phe | -4.548 | Shanghai in China |
| Salmonella enterica Serovar Typhimurium | gyrA | CY43_12185 | Fluoroquinolone (Marbofloxacin) | 259 | G - C | 87 | Asp - His | -6.38 | NA |
| Salmonella enterica Serovar Typhimurium | gyrA | CY43_12185 | Fluoroquinolone (Ciprofloxacin) | 259 | G - A | 87 | Asp - Asn | -4.56 | NA |
| Salmonella enterica Serovar Typhimurium | gyrA | CY43_12185 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) / Triclosan | 260 | A - G | 87 | Asp - Gly | -6.468 | NA |
| Salmonella enterica Serovar Typhimurium | gyrA | CY43_12185 | Nalidixic Acid | 259 | G - T | 87 | Asp - Tyr | -8.274 | NA |
| Salmonella enterica Serovar Typhimurium | gyrA | CY43_12185 | Fluoroquinolone (Ciprofloxacin) | 259 | G - A | 87 | Asp - Asn | -4.56 | Shanghai in China |
| Salmonella enterica Serovar Typhimurium | gyrA | CY43_12185 | Fluoroquinolone (Ciprofloxacin) | 259 | G - T | 87 | Asp - Tyr | -8.274 | Shanghai in China |
| Salmonella enterica Serovar Typhimurium | gyrB | CY43_19905 | Fluoroquinolone | 1388 | C - A | 463 | Ser - Tyr | -3.744 | NA |
| Salmonella enterica Serovar Typhimurium | gyrB | CY43_19905 | Fluoroquinolone | 1391 | C - T | 464 | Ser - Phe | -4.058 | Beijing in China |
| Salmonella enterica Serovar Typhimurium | gyrB | CY43_19905 | Quinolone | 1391 | TCC - TAC | 464 | Ser - Tyr | -4.064 | NA |
| Salmonella enterica Serovar Typhimurium | gyrB | CY43_19905 | Quinolone | 1391 | C - T | 464 | Ser - Phe | -4.058 | Belgium and Copenhagen and India |
| Salmonella enterica Serovar Typhimurium | gyrB | CY43_19905 | Fluoroquinolone | 1398 | A - T | 466 | Glu - Asp | -2.044 | Ghana |
| Salmonella enterica Serovar Typhimurium | gyrB | CY43_19905 | Fluoroquinolone (Ciprofloxacin) | 1398 | GAA - GAT | 466 | Glu - Asp | -2.044 | Ghana |
| Salmonella enterica Serovar Typhimurium | gyrB | CY43_19905 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 1405 | A - G | 469 | Thr - Ala | -2.939 | NA |
| Salmonella enterica Serovar Typhimurium | rpsL | CY43_17935 | Streptomycin | 125 | A - G | 42 | Lys - Arg | NA | NA |
| Salmonella enterica Serovar Typhimurium | rpsL | CY43_17935 | Streptomycin | 126 | AAA - AAC | 42 | Lys - Asn | NA | NA |
| Salmonella enterica Serovar Typhimurium | rpsL | CY43_17935 | Streptomycin | 126 | NA | 42 | Lys - Asn | NA | NA |
| Salmonella enterica Serovar Typhimurium | rpsL | CY43_17935 | Streptomycin | 125 | AAA - AGA | 42 | Lys - Arg | NA | NA |
| Salmonella enterica Serovar Typhimurium | rpsL | CY43_17935 | Streptomycin | 269 | C - T | 90 | Pro - Ser | NA | NA |
| Salmonella enterica Serovar Typhimurium | rpsL | CY43_17935 | Streptomycin | NA | AAA - AGA | NA | Lys - Arg | NA | NA |
| Salmonella enterica Serovar Typhimurium | rpsL | CY43_17935 | Streptomycin | NA | AAA - AAC | NA | Lys - Asn | NA | NA |
| Salmonella enterica Serovar Typhimurium | rpsL | CY43_17935 | Streptomycin | NA | AAA - ACA | NA | Lys - Thr | NA | NA |
| Salmonella enterica Serovar Typhimurium var 5 | gyrA | AEV03_14785 | Quinolone | 2590 | C - T | 864 | Pro - Ser | -0.172 | NA |
| Salmonella enterica Serovar Typhimurium var 5 | gyrA | AEV03_14785 | Quinolone | 259 | G - A | 87 | Asp - Asn | -4.56 | NA |
| Salmonella enterica Serovar Paratyphi A | gyrA | LW89_00955 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 248 | C - T | 83 | Ser - Phe | -4.548 | India |
| Salmonella enterica Serovar Paratyphi A | gyrA | LW89_00955 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 259 | G - A | 87 | Asp - Asn | -4.56 | India |
| Salmonella enterica Serovar Paratyphi A | gyrB | LW89_07635 | Fluoroquinolone (Ciprofloxacin) | 1391 | C - T | 464 | Ser - Phe | -4.058 | Burkina Faso |
| Salmonella sps. | gyrA | NA | Quinolone | 1744 - 1746 | NA | 582 | Leu - Gly | NA | NA |
| Salmonella sps. | gyrA | NA | Quinolone | 248 | C - A | 83 | Ser - Tyr | NA | NA |
| Salmonella sps. | gyrA | NA | Quinolone | 248 | C - T | 83 | Ser - Phe | NA | NA |
| Salmonella sps. | gyrA | NA | Quinolone | 259 | G - A | 87 | Asp - Asn | NA | NA |
| Salmonella sps. | rpsL | NA | Streptomycin | 126 | NA | 42 | Lys - Asn | NA | Moscow in Russia |
| Salmonella sps. | rpsL | NA | Streptomycin | 272 | G - A | 91 | Gly - Asp | NA | Moscow in Russia |