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DRAGdb: Drug Resistance Associated Genes

Number of mutation entries in Ureaplasma species is 17

PROVEAN score threshold is -2.5. Variants with score = or < -2.5 are considered deleterious.Variants with score > -2.5 are considered neutral.

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ORGANISM_NAMEGENE_NAMEENSEMBL_IDDRUG_NAMENUCLEOTIDE_POSITIONNUCLEOTIDE_MUTATIONAMINOACID_POSITIONAMINOACID_MUTATIONPROVEAN_SCORESAMPLE_LOCATION
Ureaplasma parvumgyrAUPA1_G0337Fluoroquinolone (Ciprofloxacin / Ofloxacin)520 - 522NA174Ser - Arg-1.272Italy
Ureaplasma parvumgyrAUPA1_G0337Fluoroquinolone (Ciprofloxacin / Ofloxacin)526C - T176Leu - Phe-3.516Italy
Ureaplasma parvumgyrAUPA1_G0337Fluoroquinolone (Ciprofloxacin / Ofloxacin)535 - 537NA179Gly - Asp-0.283Italy
Ureaplasma parvumgyrAUPA1_G0337Fluoroquinolone (Ciprofloxacin / Ofloxacin)201T - A67Phe - Ile-3.836Italy
Ureaplasma parvumgyrAUPA1_G0337Fluoroquinolone (Ciprofloxacin / Ofloxacin)232 - 234NA78Lys - Ile-6.069Italy
Ureaplasma parvumgyrBUPA1_G0336Fluoroquinolone1384C - T462Pro - Ser-7.343China
Ureaplasma parvumgyrBUPA1_G0336Quinolone1384CCA - TCA462Pro - Ser -7.343Japan
Ureaplasma parvumgyrBUPA1_G0336Fluoroquinolone (Levofloxacin)1384C - T462Pro - Ser -7.343United States
Ureaplasma parvumgyrBUPA1_G0336Fluoroquinolone1442A - G481Asn - Ser -3.88China
Ureaplasma parvumgyrBUPA1_G0336Fluoroquinolone1478C - T493Ala - Val -1.139China
Ureaplasma parvumgyrBUPA1_G0336Fluoroquinolone (Ciprofloxacin / Ofloxacin)1504G - C502Glu - Gln -0.791Italy
Ureaplasma parvumgyrBUPA1_G0336Fluoroquinolone (Ciprofloxacin / Ofloxacin)1568G - A523Arg - Gln -2.866Italy
Ureaplasma urealyticumgyrAUUR10_0088Fluoroquinolone (Ciprofloxacin / Ofloxacin)230A - T77Asp - Val-6.877Italy
Ureaplasma urealyticumgyrBUUR10_0087Fluoroquinolone (Levofloxacin)355T - C119Leu - Ser -5.655United States
Ureaplasma urealyticumgyrBUUR10_0087Fluoroquinolone (Ciprofloxacin / Ofloxacin)1270C - T424Leu - Phe -3.872Italy
Ureaplasma urealyticumgyrBUUR10_0087Fluoroquinolone (Ciprofloxacin / Ofloxacin)1485NA495Ile - Met -2.156Italy
Ureaplasma urealyticumgyrBUUR10_0087Fluoroquinolone (Ciprofloxacin / Ofloxacin)1510C - T504Leu - Phe -2.607Italy


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