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DRAGdb: Drug Resistance Associated Genes

Number of mutation entries of gyrA in Other bacteria is 282

PROVEAN score threshold is -2.5. Variants with score = or < -2.5 are considered deleterious.Variants with score > -2.5 are considered neutral.

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ORGANISM_NAMEGENE_NAMEENSEMBL_IDDRUG_NAMENUCLEOTIDE_POSITIONNUCLEOTIDE_MUTATIONAMINOACID_POSITIONAMINOACID_MUTATIONPROVEAN_SCORESAMPLE_LOCATION
Citrobacter freundiigyrAAB07_1363Fluoroquinolone (Ciprofloxacin / Levofloxacin) / Nalidixic Acid248ACC - ATC83Thr - Ile -3.545Argentina
Salmonella enterica Serovar Typhimurium var 5gyrAAEV03_14785Quinolone259G - A87Asp - Asn-4.56NA
Salmonella enterica Serovar Typhimurium var 5gyrAAEV03_14785Quinolone2590C - T864Pro - Ser-0.172NA
Salmonella enterica Serovar DublingyrAAEW76_09460Quinolone259G - T87Asp - Tyr-8.274NA
Salmonella enterica Serovar DublingyrAAEW76_09460Quinolone248C - T83Ser - Phe-4.548NA
Arcobacter butzlerigyrAAF80_03480Quinolone254C - T85Thr - Ile-3.624NA
Cutibacterium acnesgyrAAK828_05630Fluoroquinolone (Levofloxacin)299A - G100Asp - Gly -6.953NA
Cutibacterium acnesgyrAAK828_05630Fluoroquinolone (Levofloxacin)298G - C100Asp - His -6.953NA
Cutibacterium acnesgyrAAK828_05630Fluoroquinolone (Levofloxacin)295 - 297NA99Gly - Asp -6.948NA
Cutibacterium acnesgyrAAK828_05630Fluoroquinolone (Levofloxacin)313G - C105Asp - His -6.88NA
Cutibacterium acnesgyrAAK828_05630Fluoroquinolone (Levofloxacin)314A - G105Asp - Gly -6.834NA
Cutibacterium acnesgyrAAK828_05630Fluoroquinolone (Levofloxacin)302C - G101Ser - Trp -5.621NA
Cutibacterium acnesgyrAAK828_05630Fluoroquinolone (Levofloxacin)298G - A100Asp - Asn-4.967NA
Cutibacterium acnesgyrAAK828_05630Fluoroquinolone (Levofloxacin)302C - T101Ser - Leu -4.612NA
Cutibacterium acnesgyrAAK828_05630Fluoroquinolone (Levofloxacin)304G - C102Ala - Pro -3.968NA
Aeromonas veroniigyrAAO744_12715Fluoroquinolone (Ciprofloxacin / Levofloxacin / Norfloxacin)248AGC - ATC83Ser - IleNASichuan Province in China
Neisseria gonorrhoeaegyrAAW44_08030Fluoroquinolone (Ciprofloxacin)272C - T91Ser - Phe-4.456India
Escherichia coligyrAb2231Fluoroquinolone (Ciprofloxacin / Levofloxacin) / Nalidixic Acid259G - T87Asp - Tyr -8.258Argentina
Escherichia coligyrAb2231Nalidixic Acid259G - T87Asp - Tyr-8.258Taiwan
Escherichia coligyrAb2231Fluoroquinolone259G - T87Asp - Tyr -8.258Korea
Escherichia coligyrAb2231Fluoroquinolone (Ciprofloxacin / Levofloxacin) / Nalidixic Acid260A - G87Asp - Gly -6.486Argentina
Escherichia coligyrAb2231Fluoroquinolone (Ciprofloxacin)260A - G87Asp - Gly -6.486NA
Escherichia coligyrAb2231Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) / Triclosan260A - G87Asp - Gly -6.486NA
Escherichia coligyrAb2231Nalidixic Acid260NA87Asp - Gly-6.486Taiwan
Escherichia coligyrAb2231Fluoroquinolone260A - G87Asp - Gly -6.486Korea
Escherichia coligyrAb2231Fluoroquinolone (Ciprofloxacin)259G - C87Asp - His -6.331NA
Escherichia coligyrAb2231Fluoroquinolone259G - C87Asp - His -6.331Korea
Escherichia coligyrAb2231Fluoroquinolone149A - G50Tyr - Cys-5.587Mangalore in India
Escherichia coligyrAb2231Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) / Triclosan248C - T83Ser - Phe -4.559NA
Escherichia coligyrAb2231Fluoroquinolone (Ciprofloxacin / Levofloxacin) / Nalidixic Acid259G - A87Asp - Asn -4.544Argentina
Escherichia coligyrAb2231Quinolone259G - A87Asp - Asn -4.544China
Escherichia coligyrAb2231Fluoroquinolone259G - A87Asp - Asn-4.544Mangalore in India
Escherichia coligyrAb2231Fluoroquinolone (Ciprofloxacin)259G - A87Asp - Asn -4.544NA
Escherichia coligyrAb2231Nalidixic Acid259G - A87Asp - Asn-4.544Taiwan
Escherichia coligyrAb2231Fluoroquinolone259G - A87Asp - Asn -4.544Korea
Escherichia coligyrAb2231Fluoroquinolone (Ciprofloxacin / Levofloxacin) / Nalidixic Acid248TCG - TTG83Ser - Leu -4.203Argentina
Escherichia coligyrAb2231Quinolone248TCG - TTG83Ser - Leu -4.203China
Escherichia coligyrAb2231Fluoroquinolone248TCG - TTG83Ser - Leu-4.203Mangalore in India
Escherichia coligyrAb2231Fluoroquinolone (Ciprofloxacin)248TCG - TTG83Ser - Leu-4.203NA
Escherichia coligyrAb2231Fluoroquinolone (Ciprofloxacin)248TCG - TTG83Ser - Leu -4.203NA
Escherichia coligyrAb2231Nalidixic Acid248TCG - TTG83Ser - Leu-4.203Taiwan
Escherichia coligyrAb2231Fluoroquinolone248TCG - TTG83Ser - Leu -4.203Korea
Escherichia coligyrAb2231Fluoroquinolone (Ciprofloxacin / Levofloxacin) / Nalidixic Acid247TCG - GCG83Ser - Ala -2.112Argentina
Escherichia coligyrAb2231Nalidixic Acid247TCG - GCG83Ser - Ala-2.112Taiwan
Clostridium difficilegyrABG47_01785Quinolone245C - T82Thr - Ile -2.326Taiwan
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Enrofloxacin)608AAT - AGT203Asn - Ser -3.919Thailand
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone608AAT - AGT203Asn - Ser -3.919United States
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)310C - T104Pro - Ser-3.377NA
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Enrofloxacin)257ACA - ATA86Thr - Ile -3.321Thailand
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone257ACA - ATA86Thr - Ile  -3.321China
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone257ACA - ATA86Thr - Ile-3.321United States
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone257ACA - ATA86Thr - Ile -3.321NA
Campylobacter jejunigyrACJJ5050_08730Nalidixic Acid / Fluoroquinolone (Ciprofloxacin)257ACA - ATA86Thr - Ile -3.321Lima in Peru
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)257ACA - ATA86Thr - Ile-3.321Lithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)257ACA - ATA86Thr - Ile -3.321NA
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)364GCG - TCG122Ala - Ser-2.89Lithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)408GAG - GAT136Glu - Asp -2.718Lithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Enrofloxacin)64AGT - GGT22Ser - Gly-2.009Thailand
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone64AGT - GGT22Ser - Gly -2.009United States
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)64AGT - GGT22Ser - Gly -2.009Lithuania
Campylobacter jejunigyrACJJ5050_08730Nalidixic Acid256A - G86Thr - Ala -1.944Lima in Peru
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)445GTT - ATT149Val - Ile -0.305Lithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)63AAA - AAG21Lys - Lys0Lithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)72TAT - TAC24Tyr - Tyr0Lithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)84TCT - TCC28Ser - Ser0Lithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)117GAC - GAT39Asp - Asp0Lithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)177GAG - GAA59Glu - Glu0Lithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)231-232GGT - GCC78Gly - Gly0Lithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)243CAC - CAT81His - His0Lithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)330GGC - GGT110Gly - Gly0Lithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)357AGT - AGC119Ser - Ser0Lithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)360GCC - GCT120Ala - Ala0Lithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)456TAT - TAC152Tyr - Tyr0Lithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)471AGC - AGT157Ser - Ser0Lithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)483GTT - GTC161Val - Val0Lithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Enrofloxacin)617GCA - GTA206Ala - Val 0.83Thailand
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)115GCA - TCA39Ala - Ser NALithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)146AGA - AAA48Arg - Lys NALithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)189GAA - GAG63Glu - GluNALithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)207CAG - CAA69Gln - GlnNALithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)253ACA - GCA85Thr - Ala NALithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)291AAG - AAA97Lys - LysNALithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)351GTG - GTC117Val - ValNALithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)354ATA - ATC118Ile - IleNALithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)411AGC - AGT137Ser - SerNALithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)435AGC - AGT145Ser - SerNALithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone (Ciprofloxacin)447TTC - TTT149Phe - PheNALithuania
Campylobacter jejunigyrACJJ5050_08730Fluoroquinolone854G - A285Arg - LysNAUnited States
Haemophilus influenzaegyrACK45_03660Fluoroquinolone (Tosufloxacin / Levofloxacin)251C - T84Ser - Leu -4.057Tokyo in Japan
Salmonella enterica Serovar EnteritidisgyrACS37_11380Nalidixic Acid259G - T87Asp - Tyr -8.274Brazil
Salmonella enterica Serovar EnteritidisgyrACS37_11380Fluoroquinolone (Ciprofloxacin / Norfloxacin) / Nalidixic Acid259G - T87Asp - Tyr -8.274Thailand
Salmonella enterica Serovar EnteritidisgyrACS37_11380Fluoroquinolone (Ciprofloxacin)260A - G87Asp - Gly -6.468NA
Salmonella enterica Serovar EnteritidisgyrACS37_11380Fluoroquinolone (Ciprofloxacin / Norfloxacin) / Nalidixic Acid260A - G87Asp - Gly -6.468Thailand
Salmonella enterica Serovar EnteritidisgyrACS37_11380Fluoroquinolone (Ciprofloxacin / Norfloxacin) / Nalidixic Acid248C - A83Ser - Tyr -4.565Thailand
Salmonella enterica Serovar EnteritidisgyrACS37_11380Nalidixic Acid259G - A87Asp - Asn -4.56Brazil
Salmonella enterica Serovar EnteritidisgyrACS37_11380Fluoroquinolone (Ciprofloxacin / Norfloxacin) / Nalidixic Acid259G - A87Asp - Asn -4.56Thailand
Salmonella enterica Serovar EnteritidisgyrACS37_11380Nalidixic Acid248C - T83Ser - Phe -4.548Brazil
Salmonella enterica Serovar EnteritidisgyrACS37_11380Fluoroquinolone (Ciprofloxacin / Norfloxacin) / Nalidixic Acid248C - T83Ser - Phe -4.548Thailand
Salmonella enterica Serovar EnteritidisgyrACS37_11380Fluoroquinolone (Ciprofloxacin / Norfloxacin) / Nalidixic Acid248C - T83Ser - Phe -4.548Thailand
Salmonella enterica Serovar EnteritidisgyrACS37_11380Nalidixic Acid289T - C97Ser - Pro -4.509Brazil
Salmonella enterica Serovar EnteritidisgyrACS37_11380Fluoroquinolone (Ciprofloxacin / Norfloxacin) / Nalidixic Acid248AGC - ATC83Ser - Ile-4.182Thailand
Salmonella enterica Serovar TyphimuriumgyrACY43_12185Nalidixic Acid259G - T87Asp - Tyr -8.274NA
Salmonella enterica Serovar TyphimuriumgyrACY43_12185Fluoroquinolone (Ciprofloxacin)259G - T87Asp - Tyr -8.274Shanghai in China
Salmonella enterica Serovar TyphimuriumgyrACY43_12185Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) / Triclosan260A - G87Asp - Gly -6.468NA
Salmonella enterica Serovar TyphimuriumgyrACY43_12185Fluoroquinolone (Marbofloxacin)259G - C87Asp - His -6.38NA
Salmonella enterica Serovar TyphimuriumgyrACY43_12185Fluoroquinolone (Ciprofloxacin)259G - A87Asp - Asn -4.56NA
Salmonella enterica Serovar TyphimuriumgyrACY43_12185Fluoroquinolone (Ciprofloxacin)259G - A87Asp - Asn -4.56Shanghai in China
Salmonella enterica Serovar TyphimuriumgyrACY43_12185Fluoroquinolone (Marbofloxacin)248C - T83Ser - Phe -4.548NA
Salmonella enterica Serovar TyphimuriumgyrACY43_12185Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) / Triclosan248C - T83Ser - Phe -4.548NA
Salmonella enterica Serovar TyphimuriumgyrACY43_12185Fluoroquinolone (Ciprofloxacin)248C - T83Ser - Phe -4.548Shanghai in China
Streptococcus pneumoniaegyrADB40_02095Fluoroquinolone (Levofloxacin / Moxifloxacin)98C - A33Pro - His -8.38Colombia
Streptococcus pneumoniaegyrADB40_02095Fluoroquinolone (Levofloxacin / Moxifloxacin)242C - G81Ser - Trp -6.553Netherlands
Streptococcus pneumoniaegyrADB40_02095Fluoroquinolone (Levofloxacin)254A - G85Glu - Gly -5.862Aachen in Germany
Streptococcus pneumoniaegyrADB40_02095Fluoroquinolone (Levofloxacin)242C - A81Ser - Tyr -5.588Aachen in Germany
Streptococcus pneumoniaegyrADB40_02095Fluoroquinolone (Levofloxacin / Moxifloxacin)242C - A81Ser - Tyr -5.588Spain
Streptococcus pneumoniaegyrADB40_02095Fluoroquinolone (Levofloxacin / Moxifloxacin)242C - A81Ser - Tyr -5.588Taiwan
Streptococcus pneumoniaegyrADB40_02095Fluoroquinolone (Levofloxacin / Sitafloxacin / Tosufloxacin / Garenoxacin)242C - A81Ser - Tyr-5.588Tohoku area in Japan
Streptococcus pneumoniaegyrADB40_02095Fluoroquinolone (Levofloxacin)242C - T81Ser - Phe-5.583Aachen in Germany
Streptococcus pneumoniaegyrADB40_02095Fluoroquinolone (Levofloxacin / Moxifloxacin)242C - T81Ser - Phe -5.583Colombia
Streptococcus pneumoniaegyrADB40_02095Fluoroquinolone (Levofloxacin / Moxifloxacin)242C - T81Ser - Phe-5.583Spain
Streptococcus pneumoniaegyrADB40_02095Fluoroquinolone (Levofloxacin / Moxifloxacin)242C - T81Ser - Phe -5.583Sweden
Streptococcus pneumoniaegyrADB40_02095Fluoroquinolone (Levofloxacin / Moxifloxacin)242C - T81Ser - Phe -5.583Taiwan
Streptococcus pneumoniaegyrADB40_02095Fluoroquinolone (Levofloxacin / Sitafloxacin / Tosufloxacin / Garenoxacin)242C - T81Ser - Phe-5.583Tohoku area in Japan
Streptococcus pneumoniaegyrADB40_02095Fluoroquinolone (Levofloxacin)254A - C85Glu - Ala -5.175Aachen in Germany
Streptococcus pneumoniaegyrADB40_02095Fluoroquinolone (Levofloxacin)253G - A85Glu - Lys -3.517Aachen in Germany
Streptococcus pneumoniaegyrADB40_02095Fluoroquinolone (Levofloxacin / Moxifloxacin)253G - A85Glu - Lys -3.517Colombia
Streptococcus pneumoniaegyrADB40_02095Fluoroquinolone (Levofloxacin / Moxifloxacin)253G - A85Glu - Lys-3.517Spain
Streptococcus pneumoniaegyrADB40_02095Fluoroquinolone (Levofloxacin / Sitafloxacin / Tosufloxacin / Garenoxacin)253G - A85Glu - Lys-3.517Tohoku area in Japan
Streptococcus pneumoniaegyrADB40_02095Fluoroquinolone (Levofloxacin / Moxifloxacin)340 - 342NA114Ser - Gly2.033Netherlands
Streptococcus pneumoniaegyrADB40_02095Fluoroquinolone (Levofloxacin / Moxifloxacin)340 - 342NA114Ser - Gly2.033Spain
Shigella flexnerigyrADP20_4113Nalidixic Acid / Fluoroquinolone (Norfloxacin)239CAT - CCT80His - Pro-9.651Jiangsu Province of China
Shigella flexnerigyrADP20_4113Nalidixic Acid / Fluoroquinolone (Norfloxacin)260GAC - GTC87Asp - Val -8.27Jiangsu Province of China
Shigella flexnerigyrADP20_4113Nalidixic Acid / Fluoroquinolone (Norfloxacin)259GAC - TAC87Asp - Tyr -8.258Jiangsu Province of China
Shigella flexnerigyrADP20_4113Nalidixic Acid / Fluoroquinolone (Norfloxacin)260GAC - GCC87Asp - Ala -7.306Jiangsu Province of China
Shigella flexnerigyrADP20_4113Nalidixic Acid / Fluoroquinolone (Norfloxacin)260GAC - GGC87Asp - Gly -6.486Jiangsu Province of China
Shigella flexnerigyrADP20_4113Nalidixic Acid / Fluoroquinolone (Norfloxacin)171AAT - AAA57Asn - Lys-5.764Jiangsu Province of China
Shigella flexnerigyrADP20_4113Nalidixic Acid / Fluoroquinolone (Norfloxacin)259GAC - AAC87Asp - Asn -4.544Jiangsu Province of China
Shigella flexnerigyrADP20_4113Nalidixic Acid / Fluoroquinolone (Norfloxacin)248TCG - TTG83Ser - Leu -4.203Jiangsu Province of China
Shigella flexnerigyrADP20_4113Nalidixic Acid / Fluoroquinolone (Norfloxacin)631CAC - TAC211His - Tyr1.544Jiangsu Province of China
Francisella novicidagyrADR83_750Fluoroquinolone1573 - 1575NA525Ser - Deletion-9.364NA
Francisella novicidagyrADR83_750Fluoroquinolone1570 - 1572NA524Glu - Deletion-8.674NA
Francisella novicidagyrADR83_750Fluoroquinolone259G - T87Asp - Tyr -8.465NA
Francisella novicidagyrADR83_750Fluoroquinolone128C - A43Pro - His -8.378NA
Francisella novicidagyrADR83_750Fluoroquinolone260A - G87Asp - Gly -6.587NA
Francisella tularensisgyrADR85_1299Fluoroquinolone259G - T87Asp - Tyr -8.615NA
Francisella tularensisgyrADR85_1299Fluoroquinolone248ACC - ATC83Thr - Ile-4.003NA
Francisella tularensisgyrADR85_1299Fluoroquinolone248C - A83Thr - Lys -3.172NA
Moraxella catarrhalisgyrADR90_841Fluoroquinolone (Levofloxacin / Sitafloxacin / Tosufloxacin / Garenoxacin)239C - T80Thr - Ile-3.769Tohoku area in Japan
Providencia stuartiigyrADR96_3611Fluoroquinolone (Ciprofloxacin / Levofloxacin) / Nalidixic Acid248AGC - ATC83Ser - Ile -4.06Argentina
Providencia stuartiigyrADR96_3611Fluoroquinolone248AGC - ATC83Ser - Ile -4.06southern Taiwan
Providencia stuartiigyrADR96_3611Fluoroquinolone (Ciprofloxacin / Levofloxacin) / Nalidixic Acid247 - 249NA83Ser - Arg -3.596Argentina
Enterococcus faecalisgyrAEE55_10450Fluoroquinolone260A - G87Glu - Gly -5.973Gyeonggi Province in Korea
Enterococcus faecalisgyrAEE55_10450Fluoroquinolone248C - A83Ser - Tyr -5.566Gyeonggi Province in Korea
Enterococcus faecalisgyrAEE55_10450Fluoroquinolone248C - T83Ser - Phe -5.561Gyeonggi Province in Korea
Enterococcus faecalisgyrAEE55_10450Fluoroquinolone248AGC - ATC83Ser - Ile -5.514Gyeonggi Province in Korea
Enterococcus faecalisgyrAEE55_10450Fluoroquinolone247 - 249NA83Ser - Arg-4.642Gyeonggi Province in Korea
Staphylococcus epidermidisgyrAEL82_09050Fluoroquinolone251C - A84Ser - Tyr -5.024NA
Staphylococcus epidermidisgyrAEL82_09050Fluoroquinolone251C - T84Ser - Phe -4.996NA
Shigella sonneigyrAERS127223_04184Fluoroquinolone260GAC - GCC87Asp - Gly -6.486Jiangsu Province of China
Shigella sonneigyrAERS127223_04184Fluoroquinolone259GAC - AAC87Asp - Asn -4.544Jiangsu Province of China
Shigella sonneigyrAERS127223_04184Fluoroquinolone248TCG - TTG83Ser - Leu-4.203Jiangsu Province of China
Salmonella enterica Serovar TyphigyrAERS326222_03263Fluoroquinolone (Ciprofloxacin)260A - G87Asp - Gly -6.468Kolkata in India
Salmonella enterica Serovar TyphigyrAERS326222_03263Nalidixic Acid / Fluoroquinolone (Ciprofloxacin)259G - A87Asp - Asn -4.56India
Salmonella enterica Serovar TyphigyrAERS326222_03263Fluoroquinolone (Ciprofloxacin)259G - A87Asp - Asn -4.56Kolkata in India
Salmonella enterica Serovar TyphigyrAERS326222_03263Fluoroquinolone (Ciprofloxacin)259G - A87Asp - Asn -4.56NA
Salmonella enterica Serovar TyphigyrAERS326222_03263Nalidixic Acid / Fluoroquinolone (Ciprofloxacin)248C - T83Ser - Phe-4.548India
Salmonella enterica Serovar TyphigyrAERS326222_03263Fluoroquinolone (Ciprofloxacin)248C - T83Ser - Phe -4.548Kolkata in India
Salmonella enterica Serovar TyphigyrAERS326222_03263Fluoroquinolone (Ciprofloxacin)248C - T83Ser - Phe-4.548NA
Shigella flexneri 2agyrAERS574920_03941Fluoroquinolone259G - T87Asp - Tyr -8.258Northwest China
Shigella flexneri 2agyrAERS574920_03941Fluoroquinolone259G - A87Asp - Asn -4.544Northwest China
Shigella flexneri 2agyrAERS574920_03941Fluoroquinolone248TCG - TTG83Ser - Leu -4.203Northwest China
Actinotignum schaaliigyrAFB03_06620Fluoroquinolone (Ciprofloxacin)247TCG - GCG83Ser - Ala NANA
Propionibacterium acnesgyrAFB41_0385Fluoroquinolone314A - G105Asp - Gly -6.834Japan
Propionibacterium acnesgyrAFB41_0385Fluoroquinolone302C - G101Ser - Trp -5.621Japan
Propionibacterium acnesgyrAFB41_0385Fluoroquinolone302C - T101Ser - Leu-4.612Japan
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)224G - T75Gly - Val -8.823Dominican Republic
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)562C - T188Pro - Ser-7.747Kathmandu in Nepal
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)296A - T99Asp - Val-7.389Kathmandu in Nepal
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)271G - T91Asp - Tyr -7.358Dominican Republic
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone271G - T91Asp - Tyr-7.358France
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)271G - T91Asp - Tyr-7.358Indonesia
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)271G - T91Asp - Tyr -7.358Kathmandu in Nepal
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)293A - T98Gln - Leu -6.862Dominican Republic
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)445T - G149Phe - Val-6.445Dominican Republic
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)272A - G91Asp - Gly -5.952Dominican Republic
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone272A - G91Asp - Gly-5.952France
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)272A - G91Asp - Gly -5.952Indonesia
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)272A - G91Asp - Gly -5.952Kathmandu in Nepal
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone271G - C91Asp - His-5.547France
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)173A - G58Glu - Gly-4.962Dominican Republic
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)589 - 591NA197Ala - Phe -4.635Dominican Republic
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone262G - C88Ala - Pro-4.55France
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)262G - C88Ala - Pro-4.55Kathmandu in Nepal
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)290C - T97Ala - Val -3.915Dominican Republic
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)271G - A91Asp - Asn -3.901Dominican Republic
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone271G - A91Asp - Asn-3.901France
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)271G - A91Asp - Asn -3.901Indonesia
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)271G - A91Asp - Asn -3.901Kathmandu in Nepal
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)271G - A91Asp - Asn -3.901Venezuela
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)433G - A145Asp - Asn -3.359Dominican Republic
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)485T - C162Ile - Thr-3.229Dominican Republic
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)580A - T194Ile - Phe -3.21Dominican Republic
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)385G - A129Ala - Thr-2.994Indonesia
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)579A - T193Glu - Asp-2.9Dominican Republic
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)389G - A130Arg - Lys-2.06Kathmandu in Nepal
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)259A - T87Asn - Tyr -1.909Indonesia
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)481G - A161Asp - Asn-1.475Indonesia
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)260A - T87Asn - Ile -1.116Dominican Republic
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)260A - T87Asn - Ile -1.116Indonesia
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)260A - T87Asn - Ile-1.116Kathmandu in Nepal
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)260A - T87Asn - Ile -1.116Venezuela
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)261NA87Asn - Lys -0.82Dominican Republic
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone261C - A87Asn - Lys-0.82France
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone261C - G87Asn - Lys-0.82France
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)261NA87Asn - Lys -0.82Indonesia
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)261NA87Asn - Lys -0.82Kathmandu in Nepal
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)187T - C63Ser - Pro -0.772Kathmandu in Nepal
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)419G - A140Arg - Lys -0.57Indonesia
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)574G - A192Asp - Asn -0.116Indonesia
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)259 - 261NA87Asn - Ala -0.011Dominican Republic
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)514G - A172Val - Ile0.232Kathmandu in Nepal
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)401C - T134Ala - Val2.099Dominican Republic
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)260A - C87Asn - Thr2.101Dominican Republic
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)260A - C87Asn - Thr 2.101Venezuela
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)100G - A34Asp - AsnNAIndonesia
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)100G - T34Asp - TyrNAIndonesia
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone260C - T87Thr - IleNAFrance
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)1303G - A435Asp - AsnNADominican Republic
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)1435 - 1437NA479Ser - GlyNADominican Republic
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)1435 - 1437NA479Ser - Gly NADominican Republic
Helicobacter pylorigyrAHP2RS_00240 / HP2RS_00245Fluoroquinolone (Levofloxacin)1435 - 1437NA479Ser - Gly NAIndonesia
Bacteroides fragilisgyrAIB64_02590Fluoroquinolone245C - T82Ser - Phe -5.083Hungary
Serratia marcescensgyrAIY40_03600Fluoroquinolone (Ciprofloxacin / Levofloxacin) / Nalidixic Acid247 - 249NA83Ser - Arg -3.597Argentina
Morganella morganiigyrALR61_04405Fluoroquinolone (Ciprofloxacin / Levofloxacin) / Nalidixic Acid247 - 249NA83Ser - Arg NAArgentina
Morganella morganiigyrALR61_04405Fluoroquinolone (Ciprofloxacin / Levofloxacin) / Nalidixic Acid248AGC - ATC83Ser - Ile NAArgentina
Salmonella enterica Serovar Paratyphi AgyrALW89_00955Nalidixic Acid / Fluoroquinolone (Ciprofloxacin)259G - A87Asp - Asn -4.56India
Salmonella enterica Serovar Paratyphi AgyrALW89_00955Nalidixic Acid / Fluoroquinolone (Ciprofloxacin)248C - T83Ser - Phe -4.548India
Proteus mirabilisgyrAMC72_10645Fluoroquinolone (Ciprofloxacin / Levofloxacin) / Nalidixic Acid247 - 249NA83Ser - Arg NAArgentina
Proteus mirabilisgyrAMC72_10645Fluoroquinolone (Ciprofloxacin / Levofloxacin) / Nalidixic Acid248AGC - ATC83Ser - Ile NAArgentina
Proteus mirabilisgyrAMC72_10645Fluoroquinolone (Ciprofloxacin / Levofloxacin) / Nalidixic Acid260A - G87Glu - Gly NAArgentina
Mycoplasma genitaliumgyrAMG_004Fluoroquinolone259G - A87Asp - AsnNAJapan
Mycobacterium lepraegyrAML0006Quinolone272GCA - GTA91Ala - Val-2.41eastern Uttar Pradesh in India
Mycobacterium lepraegyrAML0006Fluoroquinolone (Ofloxacin)272C - T91Ala - Val -2.41NA
Mycobacterium lepraegyrAML0006Quinolone271G - A91Ala - Thr0.163eastern Uttar Pradesh in India
Mycobacterium lepraegyrAML0006Quinolone274T - G92Ser - Ala1.304eastern Uttar Pradesh in India
Staphylococcus pseudintermediusgyrANO89_11120Fluoroquinolone251C - T84Ser - Leu -4.988NA
Salmonella enterica Serovar IndianagyrASEEI1959_02253Fluoroquinolone (Ciprofloxacin)260A - G87Asp - Gly -6.468NA
Salmonella enterica Serovar IndianagyrASEEI1959_02253Fluoroquinolone (Ciprofloxacin)248C - T83Ser - Phe -4.548NA
Salmonella enterica Serovar InfantisgyrASIN_02308Fluoroquinolone (Ciprofloxacin)259G - T87Asp - Tyr-8.274United States
Klebsiella oxytocagyrASK88_04214Fluoroquinolone (Ciprofloxacin / Levofloxacin) / Nalidixic Acid248ACC - ATC83Thr - Ile NAArgentina
Salmonella enterica Serovar KentuckygyrATJ54_10510Quinolone248C - T83Ser - Phe NAEthiopia
Salmonella enterica Serovar KentuckygyrATJ54_10510Quinolone248C - A83Ser - Tyr NAEthiopia
Salmonella enterica Serovar KentuckygyrATJ54_10510Quinolone260A - G87Asp - Gly NAEthiopia
Ureaplasma parvumgyrAUPA1_G0337Fluoroquinolone (Ciprofloxacin / Ofloxacin)232 - 234NA78Lys - Ile-6.069Italy
Ureaplasma parvumgyrAUPA1_G0337Fluoroquinolone (Ciprofloxacin / Ofloxacin)201T - A67Phe - Ile-3.836Italy
Ureaplasma parvumgyrAUPA1_G0337Fluoroquinolone (Ciprofloxacin / Ofloxacin)526C - T176Leu - Phe-3.516Italy
Ureaplasma parvumgyrAUPA1_G0337Fluoroquinolone (Ciprofloxacin / Ofloxacin)520 - 522NA174Ser - Arg-1.272Italy
Ureaplasma parvumgyrAUPA1_G0337Fluoroquinolone (Ciprofloxacin / Ofloxacin)535 - 537NA179Gly - Asp-0.283Italy
Ureaplasma urealyticumgyrAUUR10_0088Fluoroquinolone (Ciprofloxacin / Ofloxacin)230A - T77Asp - Val-6.877Italy
Campylobacter coligyrAVC76_04995Fluoroquinolone (Enrofloxacin)257ACT - ATT86Thr - Ile -3.687Thailand
Campylobacter coligyrAVC76_04995Fluoroquinolone257ACT - ATT86Thr - Ile -3.687United States
Campylobacter coligyrAVC76_04995Fluoroquinolone257ACT - ATT86Thr - Ile -3.687NA
Corynebacterium striatumgyrAWU85_09410Fluoroquinolone272A - C91Asp - Ala -7.803Sousse in Tunisia
Corynebacterium striatumgyrAWU85_09410Fluoroquinolone272A - G91Asp - Gly -6.768Sousse in Tunisia
Corynebacterium striatumgyrAWU85_09410Fluoroquinolone260C - A87Ser - Tyr -4.524Sousse in Tunisia
Corynebacterium striatumgyrAWU85_09410Fluoroquinolone260C - T87Ser - Phe -4.522Sousse in Tunisia
Corynebacterium striatumgyrAWU85_09410Fluoroquinolone259T - G87Ser - Ala -1.338Sousse in Tunisia
Mycobacterium fortuitumgyrAXA26_00080Fluoroquinolone (Moxifloxacin)272TCG - TTG91Ser - Leu-4.259China
Mycobacterium fortuitumgyrAXA26_00080Fluoroquinolone (Moxifloxacin)283AGC - GGC95Ser - GlyNAChina
Mycobacterium fortuitumgyrAXA26_00080Fluoroquinolone (Moxifloxacin)284A - G95Asp - Gly-6.768Guangzhou in China
Mycobacterium fortuitumgyrAXA26_00080Fluoroquinolone (Moxifloxacin)272C - T91Ser - Leu-4.259Guangzhou in China
Salmonella sps.gyrANAQuinolone248C - A83Ser - Tyr NANA
Salmonella sps.gyrANAQuinolone248C - T83Ser - PheNANA
Avian-pathogenic Escherichia coligyrANAFluoroquinolone (Ciprofloxacin)248TCG - TTG83Ser - LeuNAEgypt
Shigella sps.gyrANAQuinolone247TCG - GCG83Ser - Ala NATehran in Iran
Shigella sps.gyrANAQuinolone248TCG - TTG83Ser - LeuNATehran in Iran
Campylobacter sps.gyrANANalidixic Acid / Fluoroquinolone (Ciprofloxacin)257C - T86Thr - IleNANA
Salmonella sps.gyrANAQuinolone259G - A87Asp - Asn NANA
Avian-pathogenic Escherichia coligyrANAFluoroquinolone (Ciprofloxacin)259G - A87Asp - Asn NAEgypt
Shigella sps.gyrANAQuinolone260GAC - GGC87Asp - Gly NATehran in Iran
Shigella sps.gyrANAQuinolone259GAC - TAC87Asp - Tyr NATehran in Iran
Salmonella sps.gyrANAQuinolone1744 - 1746NA582Leu - GlyNANA


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