DRAGdb: Drug Resistance Associated Genes
Number of mutation entries of gyrB in Other bacteria is 168
PROVEAN score threshold is -2.5. Variants with score = or < -2.5 are considered deleterious.Variants with score > -2.5 are considered neutral.
| ORGANISM_NAME | GENE_NAME | ENSEMBL_ID | DRUG_NAME | NUCLEOTIDE_POSITION | NUCLEOTIDE_MUTATION | AMINOACID_POSITION | AMINOACID_MUTATION | PROVEAN_SCORE | SAMPLE_LOCATION |
|---|---|---|---|---|---|---|---|---|---|
| Salmonella enterica Serovar Senftenberg | gyrB | AEU05_22595 | Quinolone | 1259 | A - G | 420 | Tyr - Cys | NA | NA |
| Salmonella enterica Serovar Newport | gyrB | AEV63_16010 | Quinolone | 1310 | G - T | 437 | Arg - Leu | NA | NA |
| Bartonella bacilliformis | gyrB | BARBAKC583_1346 | Fluoroquinolone (Ciprofloxacin) | 1423 | G - A | 475 | Glu - Lys | -1.168 | NA |
| Borrelia burgdorferi | gyrB | BB_0436 | Coumermycin A1 | 198 -199 | AGA - ATT | 133 | Arg - Ile | -6.672 | NA |
| Borrelia burgdorferi | gyrB | BB_0436 | Coumermycin A1 | 198 -199 | AGA - ATT | 133 | Arg - Ile | -6.672 | NA |
| Borrelia burgdorferi | gyrB | BB_0436 | Coumermycin A1 | 397 | C - G | 133 | Arg - Gly | -6.067 | NA |
| Clostridium difficile | gyrB | BG47_01780 | Fluoroquinolone (Moxifloxacin) | 1277 | GAT - GTT | 426 | Asp - Val | -8.564 | China |
| Clostridium difficile | gyrB | BG47_01780 | Fluoroquinolone (Moxifloxacin) | 1277 | GAT - GTT | 426 | Asp - Val | -8.564 | China |
| Clostridium difficile | gyrB | BG47_01780 | Fluoroquinolone | 1277 | GAT - GTT | 426 | Asp - Val | -8.564 | NA |
| Clostridium difficile | gyrB | BG47_01780 | Fluoroquinolone (Ciprofloxacin / Moxifloxacin) | 1340 | CGA - CTA | 447 | Arg - Leu | -6.331 | France |
| Clostridium difficile | gyrB | BG47_01780 | Fluoroquinolone (Moxifloxacin) | 1276 | GAT - AAT | 426 | Asp - Asn | -4.341 | China |
| Clostridium difficile | gyrB | BG47_01780 | Fluoroquinolone (Ciprofloxacin / Moxifloxacin) | 1276 | GAT - AAT | 426 | Asp - Asn | -4.341 | France |
| Clostridium difficile | gyrB | BG47_01780 | Fluoroquinolone (Moxifloxacin) | 1396 | G - A | 466 | Glu - Lys | -3.238 | Pittsburgh in United States |
| Clostridium difficile | gyrB | BG47_01780 | Fluoroquinolone | 1096 | TCA - GCA | 366 | Ser - Ala | -0.464 | Shanghai in China |
| Clostridium difficile | gyrB | BG47_01780 | Fluoroquinolone (Moxifloxacin) | 1096 | T - G | 366 | Ser - Ala | NA | China |
| Clostridium difficile | gyrB | BG47_01780 | Fluoroquinolone (Moxifloxacin) | 1276 | GAT - AAT | 426 | Asp - Asn | NA | Brazil |
| Clostridium difficile | gyrB | BG47_01780 | Fluoroquinolone (Moxifloxacin) | 1276 | GAT - AAT | 426 | Asp - Asn | NA | China |
| Clostridium difficile | gyrB | BG47_01780 | Fluoroquinolone (Moxifloxacin) | 1276 | GAT - AAT | 426 | Asp - Asn | NA | Pittsburgh in United States |
| Clostridium difficile | gyrB | BG47_01780 | Fluoroquinolone | 1276 | GAT - AAT | 426 | Asp - Asn | NA | Shanghai in China |
| Campylobacter jejuni | gyrB | CJJ5050_15010 | Fluoroquinolone (Ciprofloxacin) | 1296 | AGA - AGG | 432 | Arg - Arg | 0 | Beijing in China |
| Campylobacter jejuni | gyrB | CJJ5050_15010 | Fluoroquinolone (Ciprofloxacin) | 1308 | TTC - TTT | 436 | Phe - Phe | 0 | Beijing in China |
| Campylobacter jejuni | gyrB | CJJ5050_15010 | Fluoroquinolone (Ciprofloxacin) | 1359 | CTA - TTA | 454 | Leu - Leu | 0 | Beijing in China |
| Campylobacter jejuni | gyrB | CJJ5050_15010 | Fluoroquinolone (Ciprofloxacin) | 1413 | GGC - GGT | 471 | Gly - Gly | 0 | Beijing in China |
| Campylobacter jejuni | gyrB | CJJ5050_15010 | Fluoroquinolone (Ciprofloxacin) | 1449 | CTT - CTC | 483 | Leu - Leu | 0 | Beijing in China |
| Campylobacter jejuni | gyrB | CJJ5050_15010 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 389 | C - T | NA | NA | NA | Senegal |
| Campylobacter jejuni | gyrB | CJJ5050_15010 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 403 | A - G | NA | NA | NA | Senegal |
| Campylobacter jejuni | gyrB | CJJ5050_15010 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 436 | C - T | NA | NA | NA | Senegal |
| Campylobacter jejuni | gyrB | CJJ5050_15010 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 454 | C - T | NA | NA | NA | Senegal |
| Campylobacter jejuni | gyrB | CJJ5050_15010 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 469 | T - C | NA | NA | NA | Senegal |
| Haemophilus influenzae | gyrB | CK45_02875 | Quinolone | 1400 | C - A | 467 | Ser - Tyr | -4.084 | Japan |
| Haemophilus influenzae | gyrB | CK45_02875 | Quinolone | 1287 | NA | 429 | Asp - Glu | -2.79 | Japan |
| Haemophilus influenzae | gyrB | CK45_02875 | Quinolone | 1199 | C - T | 400 | Ala - Val | -2.564 | Japan |
| Haemophilus influenzae | gyrB | CK45_02875 | Novobiocin | 262 | G - T | 88 | Asp - Tyr | NA | NA |
| Salmonella enterica Serovar Enteritidis | gyrB | CS37_18835 | Fluoroquinolone | 1398 | A - T | 466 | Glu - Asp | -2.044 | Beijing in China |
| Salmonella enterica Serovar Enteritidis | gyrB | CS37_18835 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 1398 | A - T | 466 | Glu - Asp | -2.044 | NA |
| Salmonella enterica Serovar Typhimurium | gyrB | CY43_19905 | Quinolone | 1391 | TCC - TAC | 464 | Ser - Tyr | -4.064 | NA |
| Salmonella enterica Serovar Typhimurium | gyrB | CY43_19905 | Quinolone | 1391 | C - T | 464 | Ser - Phe | -4.058 | Belgium and Copenhagen and India |
| Salmonella enterica Serovar Typhimurium | gyrB | CY43_19905 | Fluoroquinolone | 1391 | C - T | 464 | Ser - Phe | -4.058 | Beijing in China |
| Salmonella enterica Serovar Typhimurium | gyrB | CY43_19905 | Fluoroquinolone | 1388 | C - A | 463 | Ser - Tyr | -3.744 | NA |
| Salmonella enterica Serovar Typhimurium | gyrB | CY43_19905 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 1405 | A - G | 469 | Thr - Ala | -2.939 | NA |
| Salmonella enterica Serovar Typhimurium | gyrB | CY43_19905 | Fluoroquinolone | 1398 | A - T | 466 | Glu - Asp | -2.044 | Ghana |
| Salmonella enterica Serovar Typhimurium | gyrB | CY43_19905 | Fluoroquinolone (Ciprofloxacin) | 1398 | GAA - GAT | 466 | Glu - Asp | -2.044 | Ghana |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone (Moxifloxacin) | 1685 - 1695 | CTTCCAGGGAA - Deletion | 412 - 414 | Leu Pro Gly - Deletion | -27.035 | NA |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone (Levofloxacin) | 1304 | A - T | 435 | Asp - Val | -8.28 | NA |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone (Moxifloxacin) | 1360 | C - T | 454 | Pro - Ser | -7.269 | NA |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone (Levofloxacin) | 1456 - 1458 | NA | 486 | Gly - Glu | -6.724 | Germany |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone (Levofloxacin) | 1339 | C - T | 447 | Arg - Cys | -6.297 | Germany |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone (Ciprofloxacin) | 1330 | G - A | 444 | Gly - Ser | -5.445 | NA |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone (Ciprofloxacin) | 1335 | NA | 445 | Arg - Ser | -5.442 | NA |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone (Ciprofloxacin) | 1303 | G - A | 435 | Asp - Asn | -4.37 | London in United Kingdom |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone (Levofloxacin) | 1305 | NA | 435 | Asp - Glu | -3.656 | Germany |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone | 1305 | NA | 435 | Asp - Glu | -3.656 | Singapore |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone | 1169 | C - T | 390 | Ala - Val | -3.607 | Philippines |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone (Levofloxacin) | 889 | G - T | 297 | Ala - Ser | -2.547 | NA |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone | 1268 | A - C | 423 | Asn - Thr | -2.338 | Philippines |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone (Gemifloxacin / Gatifloxacin / Moxifloxacin) | 1420 | G - A | 474 | Glu - Lys | -2.059 | Canada |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone (Levofloxacin) | 1420 | G - A | 474 | Glu - Lys | -2.059 | Germany |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Quinolone | 1420 | G - A | 474 | Glu - Lys | -2.059 | NA |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone (Gatifloxacin) | 1420 | G - A | 474 | Glu - Lys | -2.059 | United States |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone (Trovafloxacin / Clinafloxacin) | 1216 | G - A | 406 | Gly - Ser | -1.634 | NA |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone (Levofloxacin) | 1136 | G - T | 379 | Arg - Leu | -1.342 | NA |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone (Gemifloxacin) | 1276 | G - A | 426 | Glu - Lys | -0.806 | NA |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone (Levofloxacin / Moxifloxacin) | 1306 | C - A | 436 | Leu - Ile | NA | NA |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone (Levofloxacin) | 1457 | A - G | 486 | Glu - Gly | NA | NA |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone | 1152 | A - G | NA | NA | NA | NA |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone | 1158 | G - A | NA | NA | NA | NA |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone | 1356 | C - T | NA | NA | NA | NA |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone | 1383 | C - T | NA | NA | NA | NA |
| Streptococcus pneumoniae | gyrB | DB40_05905 / DB40_10290 | Fluoroquinolone | 1416 | G - A | NA | NA | NA | NA |
| Yersinia enterocolitica | gyrB | DJ60_2678 | Fluoroquinolone | 1390 - 1392 | NA | 464 | Ser - Lys | -2.596 | NA |
| Streptococcus iniae | gyrB | DQ08_05990 / DQ08_04155 | Novobiocin | 1905 | AGA - AGC | 635 | Arg - Ser | -4.044 | Israel |
| Francisella novicida | gyrB | DR83_1114 | Fluoroquinolone | 1462 - 1464 | NA | 488 | Lys - deletion | -9.746 | NA |
| Francisella novicida | gyrB | DR83_1114 | Fluoroquinolone | 1461 | NA | 487 | Asp - Glu | -1.388 | NA |
| Francisella novicida | gyrB | DR83_1114 | Fluoroquinolone | 1396 - 1398 | NA | 466 | Pro - Insertion | NA | NA |
| Moraxella catarrhalis | gyrB | DR90_72 | Quinolone | 1481 | A - G | 494 | Asp - Gly | -3.306 | Japan |
| Salmonella enterica Serovar Typhi | gyrB | ERS326222_04129 | Fluoroquinolone (Ciprofloxacin) | 1391 | C - A | 464 | Ser - Tyr | -4.064 | France |
| Salmonella enterica Serovar Typhi | gyrB | ERS326222_04129 | Fluoroquinolone (Ciprofloxacin) | 1391 | C - A | 464 | Ser - Tyr | -4.064 | India |
| Salmonella enterica Serovar Typhi | gyrB | ERS326222_04129 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 1391 | C - A | 464 | Ser - Tyr | -4.064 | India |
| Salmonella enterica Serovar Typhi | gyrB | ERS326222_04129 | Fluoroquinolone (Ciprofloxacin) | 1391 | C - A | 464 | Ser - Tyr | -4.064 | NA |
| Salmonella enterica Serovar Typhi | gyrB | ERS326222_04129 | Fluoroquinolone (Ciprofloxacin) | 1391 | C - T | 464 | Ser - Phe | -4.058 | France |
| Salmonella enterica Serovar Typhi | gyrB | ERS326222_04129 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 1391 | C - T | 464 | Ser - Phe | -4.058 | India |
| Salmonella enterica Serovar Typhi | gyrB | ERS326222_04129 | Fluoroquinolone (Ciprofloxacin) | 1391 | C - T | 464 | Ser - Phe | -4.058 | NA |
| Salmonella enterica Serovar Typhi | gyrB | ERS326222_04129 | Fluoroquinolone (Ciprofloxacin) | 1391 | TCC - TTC | 464 | Ser - Phe | -4.058 | Sub-Saharan Africa |
| Salmonella enterica Serovar Typhi | gyrB | ERS326222_04129 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 1389 - 1392 | NA | 464 | Ser - Thr | -2.039 | India |
| Salmonella enterica Serovar Typhi | gyrB | ERS326222_04129 | Fluoroquinolone (Ciprofloxacin) | 1390 - 1392 | NA | 464 | Ser - Thr | -2.039 | NA |
| Propionibacterium acnes | gyrB | FB41_0386 | Fluoroquinolone | 1483 | C - T | 495 | Pro - Ser | -7.557 | NA |
| Propionibacterium acnes | gyrB | FB41_0386 | Fluoroquinolone | 1428 | NA | 476 | Asp - Glu | -3.849 | NA |
| Streptococcus agalactiae (group B streptococcus [GBS]) | gyrB | GBS222_0521 | Fluoroquinolone (Levofloxacin) | 1448 - 1500 | NA | 500 | Tyr - Gln | -7.072 | Italy |
| Streptococcus agalactiae (group B streptococcus [GBS]) | gyrB | GBS222_0521 | Fluoroquinolone (Levofloxacin) | 1382 | T - A | 461 | Ile - Asn | -6.306 | Italy |
| Streptococcus agalactiae (group B streptococcus [GBS]) | gyrB | GBS222_0521 | Fluoroquinolone (Levofloxacin) | 1487 | C - T | 496 | Ser - Leu | -3.938 | Italy |
| Streptococcus agalactiae (group B streptococcus [GBS]) | gyrB | GBS222_0521 | Fluoroquinolone (Levofloxacin) | 1451 | C - T | 484 | Ala - Val | -3.587 | Italy |
| Streptococcus agalactiae (group B streptococcus [GBS]) | gyrB | GBS222_0521 | Fluoroquinolone (Levofloxacin) | 928 - 930 | NA | 310 | Lys - Arg | -1.473 | Italy |
| Streptococcus agalactiae (group B streptococcus [GBS]) | gyrB | GBS222_0521 | Fluoroquinolone (Levofloxacin) | 1476 | NA | 492 | Asp - Glu | -1.215 | Italy |
| Streptococcus agalactiae (group B streptococcus [GBS]) | gyrB | GBS222_0521 | Fluoroquinolone (Levofloxacin) | 1493 | T - C | 498 | Val - Ala | NA | Italy |
| Streptococcus agalactiae (group B streptococcus [GBS]) | gyrB | GBS222_0521 | Fluoroquinolone (Levofloxacin) | 1492 - 1494 | NA | 498 | Val - Cys | NA | Italy |
| Streptococcus agalactiae (group B streptococcus [GBS]) | gyrB | GBS222_0521 | Fluoroquinolone (Levofloxacin) | 1503 | NA | 501 | Phe - Lys | NA | Italy |
| Helicobacter pylori | gyrB | HP2RS_04012 | Fluoroquinolone (Levofloxacin) | 1388 | A - G | 463 | Glu - Gly | -4.076 | Kobe in Japan |
| Helicobacter pylori | gyrB | HP2RS_04012 | Fluoroquinolone (Levofloxacin) | 1303 | G - A | 435 | Asp - Asn | -3.651 | Kobe in Japan |
| Helicobacter pylori | gyrB | HP2RS_04012 | Fluoroquinolone | 1443 | NA | 481 | Asp - Glu | -2.802 | Korea |
| Helicobacter pylori | gyrB | HP2RS_04012 | Quinolone | 1189 - 1191 | NA | 397 | Ser - Gly | -2.29 | Beijing in China |
| Helicobacter pylori | gyrB | HP2RS_04012 | Fluoroquinolone (Norfloxacin / Levofloxacin) | 1387 | G - A | 463 | Glu - Lys | -1.878 | Japan |
| Helicobacter pylori | gyrB | HP2RS_04012 | Fluoroquinolone (Levofloxacin) | 1447 | G - A | 483 | Glu - Lys | -1.791 | Nepal |
| Helicobacter pylori | gyrB | HP2RS_04012 | Fluoroquinolone | 1369 | T - G | 457 | Ser - Ala | -1.601 | Peking in China |
| Helicobacter pylori | gyrB | HP2RS_04012 | Fluoroquinolone (Levofloxacin) | 1435 - 1437 | NA | 479 | Ser - Gly | -1.152 | Venezuela |
| Helicobacter pylori | gyrB | HP2RS_04012 | Fluoroquinolone (Levofloxacin) | 1435 - 1437 | NA | 479 | Ser - Gly | -1.152 | Indonesia |
| Helicobacter pylori | gyrB | HP2RS_04012 | Fluoroquinolone (Levofloxacin) | 1446 | NA | 482 | Ile - Met | -0.787 | Kobe in Japan |
| Helicobacter pylori | gyrB | HP2RS_04012 | Fluoroquinolone (Norfloxacin / Levofloxacin) | 481 | G - A | 161 | Ala - Thr | 1.251 | Japan |
| Helicobacter pylori | gyrB | HP2RS_04012 | Fluoroquinolone (Levofloxacin) | 1451 | G - A | 484 | Arg - Lys | 2.18 | Indonesia |
| Helicobacter pylori | gyrB | HP2RS_04012 | Fluoroquinolone | 1451 | G - A | 484 | Arg - Lys | 2.18 | Korea |
| Aeromonas hydrophila | gyrB | HR52_19550 | Novobiocin | 653 | TAC - TGC | 218 | Tyr - Cys | -8.682 | NA |
| Aeromonas hydrophila | gyrB | HR52_19550 | Novobiocin | 409 - 410 | CGC - ATC | 137 | Arg - Ser | -5.26 | NA |
| Escherichia coli | gyrB | HUS2011_4464 | Fluoroquinolone | 1372 | NA | 458 | Phe - Val | -4.932 | China |
| Escherichia coli | gyrB | HUS2011_4464 | Fluoroquinolone (Ciprofloxacin) | 1391 | C - A | 464 | Ser - Tyr | -4.21 | NA |
| Escherichia coli | gyrB | HUS2011_4464 | Fluoroquinolone (Ciprofloxacin) | 1391 | C - T | 464 | Ser - Phe | -4.209 | NA |
| Escherichia coli | gyrB | HUS2011_4464 | Fluoroquinolone | 1276 | GAT - AAT | 426 | Asp - Asn | -3.588 | NA |
| Escherichia coli | gyrB | HUS2011_4464 | Fluoroquinolone (Ciprofloxacin) | 1306 | T - C | 431 | Ser - Pro | -3.546 | NA |
| Escherichia coli | gyrB | HUS2011_4464 | Fluoroquinolone | 1339 | A - G | 447 | Lys - Glu | -2.866 | NA |
| Escherichia coli | gyrB | HUS2011_4464 | Fluoroquinolone (Ciprofloxacin) | 1339 | A - G | 447 | Lys - Glu | -2.866 | Barcelona in Spain |
| Escherichia coli | gyrB | HUS2011_4464 | Nalidixic Acid | 1339 | A - G | 447 | Lys - Glu | -2.866 | NA |
| Escherichia coli | gyrB | HUS2011_4464 | Fluoroquinolone (Ciprofloxacin) | 1398 | A - T | 466 | Glu - Asp | -2.109 | Seoul in South Korea |
| Escherichia coli | gyrB | HUS2011_4464 | Fluoroquinolone | 1402 | G - C | 468 | Ala - Pro | -2.031 | China |
| Escherichia coli | gyrB | HUS2011_4464 | Quinolone | 1475 | G - A | 492 | Ser - Asn | 0.469 | China |
| Escherichia coli | gyrB | HUS2011_4464 | Nalidixic Acid / Fluoroquinolone (Ciprofloxacin) | 1475 | G - A | 492 | Ser - Asn | 0.469 | Korea |
| Escherichia coli | gyrB | HUS2011_4464 | Fluoroquinolone (Moxifloxacin) | 1396 - 1398 | NA | 466 | Glu - Insertion | NA | NA |
| Bacillus anthracis | gyrB | HYU01_00030 / HYU01_17875 | Fluoroquinolone | 1408 | AAC - GAC | 470 | Asn - Asp | -4.409 | NA |
| Bacteroides fragilis | gyrB | IB64_15450 | Fluoroquinolone | 1243 | C - G | 415 | Leu - Val | NA | NA |
| Bacteroides fragilis | gyrB | IB64_15450 | Fluoroquinolone | 1432 | G - A | 478 | Glu - Lys | NA | NA |
| Legionella pneumophila | gyrB | lpbnt_00059 | Fluoroquinolone | 1391 | TCT - TAT | 464 | Ser - Tyr | -3.928 | Paris in France |
| Legionella pneumophila | gyrB | lpbnt_00059 | Fluoroquinolone | 1276 | GAC - AAC | 426 | Ala - Asn | NA | Paris in France |
| Morganella morganii | gyrB | LR61_13930 | Quinolone | 1391 | C - A | 464 | Ser - Tyr | -3.992 | Tunisia |
| Morganella morganii | gyrB | LR61_13930 | Quinolone | 1387 | T - G | 463 | Ser - Ala | NA | Tunisia |
| Salmonella enterica Serovar Paratyphi A | gyrB | LW89_07635 | Fluoroquinolone (Ciprofloxacin) | 1391 | C - T | 464 | Ser - Phe | -4.058 | Burkina Faso |
| Mycobacterium abscessus | gyrB | MAB_0006 | Fluoroquinolone | 1391 | NA | 464 | Ser - Asn | NA | China |
| Mycobacterium avium | gyrB | MAV_0005 | Fluoroquinolone | 6416 | CAG - CGG | 2139 | Gln - Arg | NA | China |
| Mycobacterium avium | gyrB | MAV_0005 | Fluoroquinolone | 6436 | CTC - TTC | 2146 | Leu - Phe | NA | China |
| Mycobacterium avium | gyrB | MAV_0005 | Fluoroquinolone | 6480 | ATT - ATG | 2160 | Ile - Met | NA | China |
| Mycobacterium avium | gyrB | MAV_0005 | Fluoroquinolone | 6478 | ATT - GTT | 2160 | Ile - Val | NA | China |
| Mycobacterium avium | gyrB | MAV_0005 | Fluoroquinolone | 6817 | ATC - CTC | 2273 | Ile - Leu | NA | China |
| Mycobacterium avium | gyrB | MAV_0005 | Fluoroquinolone | 6820 | ACC - GCC | 2274 | Thr - Ala | NA | China |
| Mycobacterium avium | gyrB | MAV_0005 | Fluoroquinolone | 6902 | CTG - CGG | 2301 | Leu - Arg | NA | China |
| Salmonella enterica | gyrB | MC58_18210 | Quinolone | 1391 | C - A | 464 | Ser - Tyr | NA | NA |
| Proteus mirabilis | gyrB | MC72_17355 | Fluoroquinolone | 1366 -1368 | AAG - Insertion | 456 | Lys - Insertion | NA | United States |
| Proteus mirabilis | gyrB | MC72_17355 | Fluoroquinolone | 1391 | C - T | 464 | Ser - Phe | NA | United States |
| Proteus mirabilis | gyrB | MC72_17355 | Fluoroquinolone | 1391 | C - A | 464 | Ser - Tyr | NA | United States |
| Proteus mirabilis | gyrB | MC72_17355 | Fluoroquinolone | 1391 | C - T | 464 | Ser - Phe | NA | NA |
| Proteus mirabilis | gyrB | MC72_17355 | Fluoroquinolone | 1391 | C - A | 464 | Ser - Tyr | NA | NA |
| Proteus mirabilis | gyrB | MC72_17355 | Quinolone | 1398 | A - T | 466 | Glu - Asp | NA | China |
| Proteus mirabilis | gyrB | MC72_17355 | Fluoroquinolone | 1398 | A - T | 466 | Glu - Asp | NA | United States |
| Streptococcus mitis | gyrB | SK608_0821 | Fluoroquinolone (Ciprofloxacin) | 1480 - 1482 | NA | 494 | Ser - Thr | -1.52 | Barcelona in Spain |
| Brachyspira hyodysenteriae | gyrB | SZ44_05815 | Coumermycin A1 | 232 | GGT - TGT | 78 | Gly - Cys | -8.213 | NA |
| Brachyspira hyodysenteriae | gyrB | SZ44_05815 | Coumermycin A1 | 232 | GGT - AGT | 78 | Gly - Ser | -5.475 | NA |
| Brachyspira hyodysenteriae | gyrB | SZ44_05815 | Coumermycin A1 | 496 | ACT - GCT | 166 | Thr - Ala | -4.972 | NA |
| Treponema denticola | gyrB | TDE_0002 | Coumermycin A1 | 407 | A - C | 136 | Lys - Thr | -2.981 | NA |
| Treponema denticola | gyrB | TDE_0002 | Coumermycin A1 | 406 | A - G | 136 | Lys - Glu | -1.855 | NA |
| Ureaplasma parvum | gyrB | UPA1_G0336 | Fluoroquinolone | 1384 | C - T | 462 | Pro - Ser | -7.343 | China |
| Ureaplasma parvum | gyrB | UPA1_G0336 | Quinolone | 1384 | CCA - TCA | 462 | Pro - Ser | -7.343 | Japan |
| Ureaplasma parvum | gyrB | UPA1_G0336 | Fluoroquinolone (Levofloxacin) | 1384 | C - T | 462 | Pro - Ser | -7.343 | United States |
| Ureaplasma parvum | gyrB | UPA1_G0336 | Fluoroquinolone | 1442 | A - G | 481 | Asn - Ser | -3.88 | China |
| Ureaplasma parvum | gyrB | UPA1_G0336 | Fluoroquinolone (Ciprofloxacin / Ofloxacin) | 1568 | G - A | 523 | Arg - Gln | -2.866 | Italy |
| Ureaplasma parvum | gyrB | UPA1_G0336 | Fluoroquinolone | 1478 | C - T | 493 | Ala - Val | -1.139 | China |
| Ureaplasma parvum | gyrB | UPA1_G0336 | Fluoroquinolone (Ciprofloxacin / Ofloxacin) | 1504 | G - C | 502 | Glu - Gln | -0.791 | Italy |
| Ureaplasma urealyticum | gyrB | UUR10_0087 | Fluoroquinolone (Levofloxacin) | 355 | T - C | 119 | Leu - Ser | -5.655 | United States |
| Ureaplasma urealyticum | gyrB | UUR10_0087 | Fluoroquinolone (Ciprofloxacin / Ofloxacin) | 1270 | C - T | 424 | Leu - Phe | -3.872 | Italy |
| Ureaplasma urealyticum | gyrB | UUR10_0087 | Fluoroquinolone (Ciprofloxacin / Ofloxacin) | 1510 | C - T | 504 | Leu - Phe | -2.607 | Italy |
| Ureaplasma urealyticum | gyrB | UUR10_0087 | Fluoroquinolone (Ciprofloxacin / Ofloxacin) | 1485 | NA | 495 | Ile - Met | -2.156 | Italy |
| Campylobacter coli | gyrB | VC76_00015 | Fluoroquinolone (Ciprofloxacin) | 1471 | ATG - CTG | 491 | Met - Leu | -2.397 | Switzerland |
| Coxiella burnetii | gyrB | VO67_11285 | Fluoroquinolone (Levofloxacin) | 1306 | TCG - CCG | 431 | Ser - Pro | NA | NA |
| Coxiella burnetii | gyrB | VO67_11285 | Fluoroquinolone (Levofloxacin) | 1569 | ATG - ATA | 518 | Met - Ile | NA | NA |