DRAGdb: Drug Resistance Associated Genes
Number of mutation entries of katG in Other bacteria is 10
PROVEAN score threshold is -2.5. Variants with score = or < -2.5 are considered deleterious.Variants with score > -2.5 are considered neutral.
| ORGANISM_NAME | GENE_NAME | ENSEMBL_ID | DRUG_NAME | NUCLEOTIDE_POSITION | NUCLEOTIDE_MUTATION | AMINOACID_POSITION | AMINOACID_MUTATION | PROVEAN_SCORE | SAMPLE_LOCATION |
|---|---|---|---|---|---|---|---|---|---|
| Mycobacterium africanum | KatG | CH86_03112 | Isoniazid | 944 | AGC - AAC | 315 | Ser - Asn | NA | Sierra Leone |
| Mycobacterium africanum | KatG | CH86_03112 | Isoniazid | 944 | AGC - ATC | 315 | Ser - Ile | NA | Sierra Leone |
| Mycobacterium africanum | KatG | CH86_03112 | Isoniazid | 944 | AGC - ACC | 315 | Ser - Thr | NA | Sierra Leone |
| Mycobacterium africanum | KatG | CH86_03112 | Isoniazid | 944 | AGC - ACC | 315 | Ser - Thr | NA | Uganda |
| Mycobacterium bovis BCG | KatG | Mb1943c | Isoniazid | 1142 | A - G | 381 | Asp - Gly | -6.797 | NA |
| Mycobacterium bovis BCG | KatG | Mb1943c | Isoniazid | 823 | A - C | 275 | Thr - Pro | -5.123 | NA |
| Mycobacterium bovis BCG | KatG | Mb1943c | Isoniazid | 944 | G - C | 315 | Ser - Thr | -2.853 | NA |
| Mycobacterium ulcerans | KatG | MUL_2190 | Isoniazid | 1291 - 1293 | NA | 431 | Arg - Gly | NA | NA |
| Mycobacterium ulcerans | KatG | MUL_2190 | Isoniazid | 944 | AGC - ACC | 315 | Ser - Thr | -2.918 | Kazakhstan |
| Mycobacterium ulcerans | KatG | MUL_2190 | Isoniazid | 945 | AGC - ACC | 316 | Ser - Thr | NA | Germany |