Welcome to EnPPIpred

Enteropathogen Protein Protein Interactions (PPIs) Prediction, abbreviated as "EnPPIpred", is a web server that predicts intra protein protein interaction of entheropathogen including Escherichia coli (E. coli), Salmonella Typhi, Shigella flexneri, Vibrio cholerae & Yersinia entrocolitica.Escherichia coli (E. coli) data set was used to build Support Vector Machine model.
Different features were used for generating the models including - i) Domain-Domain Association (DDA) ii) Degree (No. of Interacting partners present in a PPIs networks) iii) Amino Acid Composition (AAC) iv) Dipeptide Composition (DC) v) Hybrid Approach (DDA, degree and amino acid composition).

* Multiple PPIs option available from browse page where user can select single protein from Protein A and one or more proteins from Protein B.

 

 

 

Citations: Barman RK, Jana T, Das S, Saha S Prediction of Intra-species Protein-Protein Interactions in Enteropathogens Facilitating Systems Biology Study PLoS One. 2015 Dec 30;10(12):e0145648   PMID: 26717407