Record No:1
| ACCESS NO | D100185 |
| GENE_NAME | LOXL2 |
| DESCRIPTION | Lysyl oxidase-like 2 |
| ALIASES | LOR, LOR2, WS9-14. |
| NCBI_ENTREZ_NO | 4017 |
| UNIPROT_ACCESS_NO | Q9Y4K0 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell. |
| SAMPLE | Airway Epithelial Cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | NA |
| COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
| REFERENCE | 17919147 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | Protein-lysine 6-oxidase activity, scavenger receptor activity, copper ion binding, protein binding, electron transfer activity, oxidoreductase activity, oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor, metal ion binding, oligosaccharide binding. |
| GO_BIOLOGICAL_PROCESS | Negative regulation of transcription by RNA polymerase II, response to hypoxia, epithelial to mesenchymal transition, endothelial cell proliferation, sprouting angiogenesis, chromatin organization, DNA-templated transcription, regulation of DNA-templated transcription, cellular protein modification process, receptor-mediated endocytosis, cell adhesion, aging, positive regulation of epithelial to mesenchymal transition, peptidyl-lysine oxidation, electron transport chain, collagen fibril organization, positive regulation of chondrocyte differentiation, endothelial cell migration, negative regulation of DNA-templated transcription, response to copper ion, oxidation-reduction process, heterochromatin organization, negative regulation of stem cell population maintenance. |
| BIOGRID_INTERACTION_ID | 110201 |
| SNP_ID | - |
| DRUG_ID | 4150 |
| STRUCTURE_ID | 200329 |
| MONOCLONAL_ANTIBODY | Anti-LOXL2 antibody for Mouse, Rat, Human. |