Record No:1
| ACCESS NO | D100193 |
| GENE_NAME | EDNRA |
| DESCRIPTION | Endothelin receptor type A |
| ALIASES | ET-A, ETA, ETA-R, ETAR, ETRA, MFDA, hET-AR. |
| NCBI_ENTREZ_NO | 1909 |
| UNIPROT_ACCESS_NO | P25101 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma and effect of house dust mite allergens on human airway epithelial cell. |
| SAMPLE | Airway Epithelial Cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | NA |
| COMMENTS | This is a cell communication protein significantly upregulated in asthma. |
| REFERENCE | 17919147 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | Phosphatidylinositol phospholipase C activity, obsolete signal transducer activity, G-protein coupled receptor activity, endothelin receptor activity, protein binding. |
| GO_BIOLOGICAL_PROCESS | Branching involved in blood vessel morphogenesis, response to hypoxia, in utero embryonic development, smooth muscle contraction, signal transduction, G-protein coupled receptor signaling pathway, activation of adenylate cyclase activity, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, activation of phospholipase C activity, positive regulation of cytosolic calcium ion concentration, heart development, respiratory gaseous exchange, regulation of blood pressure, cell proliferation, regulation of glucose transmembrane transport, neural crest cell development, artery smooth muscle contraction, vasoconstriction, enteric nervous system development, head development, endothelin receptor signaling pathway, glucose transmembrane transport. |
| BIOGRID_INTERACTION_ID | 108231 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 200339 |
| MONOCLONAL_ANTIBODY | Anti-Endothelin A Receptor/ET-A antibody for Human, Mouse. |