Record No:1
| ACCESS NO | D100890 |
| GENE_NAME | CCL11 |
| DESCRIPTION | C-C motif chemokine ligand 11 |
| ALIASES | SCYA11. |
| NCBI_ENTREZ_NO | 6356 |
| UNIPROT_ACCESS_NO | P51671 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Allergic Rhinitis |
| SAMPLE | Nasal Mucosa |
| TECHNIQUES | cDNA Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | NA |
| COMMENTS | An important chemokine involved in tissue inflammation. Was upregulated in Allergic Rhinitis. |
| REFERENCE | 17982926 |
| IMMUNITY_TERM | Yes |
| GO_MOLECULAR_FUNCTION | Cytokine activity, protein binding, chemokine activity, CCR3 chemokine receptor binding, protein dimerization activity, receptor ligand activity, CCR chemokine receptor binding. |
| GO_BIOLOGICAL_PROCESS | Positive regulation of endothelial cell proliferation, chronic inflammatory response, monocyte chemotaxis, mast cell chemotaxis, protein phosphorylation, cellular calcium ion homeostasis, chemotaxis, inflammatory response, immune response, cytoskeleton organization, actin filament organization, cell adhesion, signal transduction, G-protein coupled receptor signaling pathway, regulation of cell shape, response to radiation, response to virus, regulation of signaling receptor activity, cytokine-mediated signaling pathway, positive regulation of cell migration, neutrophil chemotaxis, positive regulation of actin filament polymerization, response to interleukin-13, positive regulation of GTPase activity, positive regulation of angiogenesis, eosinophil chemotaxis, lymphocyte chemotaxis, branching involved in mammary gland duct morphogenesis, mammary duct terminal end bud growth, chemokine-mediated signaling pathway, ERK1 and ERK2 cascade, positive regulation of ERK1 and ERK2 cascade, response to interleukin-4, cellular response to interferon-gamma, cellular response to interleukin-1, cellular response to tumor necrosis factor. |
| BIOGRID_INTERACTION_ID | 112259 |
| SNP_ID | 301156 |
| DRUG_ID | 4131 |
| STRUCTURE_ID | 201196 201197 |
| MONOCLONAL_ANTIBODY | Anti-Eotaxin antibody for Human. |