Record No:1
| ACCESS NO | D101959 |
| GENE_NAME | TAPBP |
| DESCRIPTION | TAP binding protein |
| ALIASES | NGS17, TAPA, TPN, TPSN. |
| NCBI_ENTREZ_NO | 6892 |
| UNIPROT_ACCESS_NO | O15533 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma( Mite sensitized asthma in children) |
| SAMPLE | Peripheral Blood Mononuclear Cells (PBMCs) |
| TECHNIQUES | Microarray and RT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | NA |
| COMMENTS | Upregulated in asthmatic children. Involved in cellular function and maintenance. |
| REFERENCE | 19187333 |
| IMMUNITY_TERM | Yes |
| GO_MOLECULAR_FUNCTION | Protein binding, peptide antigen-transporting ATPase activity, MHC class I protein binding, peptide antigen binding, TAP1 binding, TAP2 binding, unfolded protein binding. |
| GO_BIOLOGICAL_PROCESS | MHC class I protein complex assembly, antigen processing and presentation of peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I ( TAP-dependent), retrograde vesicle-mediated transport ( Golgi to ER), immune response, regulation of gene expression, peptide transport, antigen processing and presentation of endogenous peptide antigen via MHC class I, amide transport, peptide antigen stabilization, regulation of protein complex stability, protein-containing complex assembly, vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane. |
| BIOGRID_INTERACTION_ID | 112755 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 200685 |
| MONOCLONAL_ANTIBODY | - |