Record No:1
| ACCESS NO | D102168 |
| GENE_NAME | MIR126 |
| DESCRIPTION | MicroRNA 126 |
| ALIASES | MIRN126, miRNA126, mir-126, miR-126. |
| NCBI_ENTREZ_NO | 406913 |
| UNIPROT_ACCESS_NO | - |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma and Allergic Rhinitis |
| SAMPLE | Blood Plasma |
| TECHNIQUES | RT-PCR Array |
| OMICS | Genomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | NA |
| COMMENTS | Increased blood plasma level of miR-126 was found in both allergic rhinitis and asthma patients as compared to healthy subjects. |
| REFERENCE | 27025347 |
| IMMUNITY_TERM | Yes |
| GO_MOLECULAR_FUNCTION | RNA polymerase II core binding, mRNA binding involved in posttranscriptional gene silencing. |
| GO_BIOLOGICAL_PROCESS | Positive regulation of phosphatidylinositol 3-kinase signaling, gene silencing by miRNA, positive regulation of MAPK cascade, positive regulation of blood vessel endothelial cell migration, positive regulation of Notch signaling pathway, positive regulation of angiogenesis, negative regulation of inflammatory response, positive regulation of protein kinase B signaling, positive regulation of ERK1 and ERK2 cascade, cellular response to hypoxia, cellular response to laminar fluid shear stress, positive regulation of cell migration involved in sprouting angiogenesis, positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis, positive regulation of sprouting angiogenesis, positive regulation of vasculature development, negative regulation of vascular endothelial cell proliferation, positive regulation of vascular endothelial cell proliferation, negative regulation of endothelial cell apoptotic process. |
| BIOGRID_INTERACTION_ID | 135762 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | - |
| MONOCLONAL_ANTIBODY | - |