Record No:1
| ACCESS NO | D102196 |
| GENE_NAME | TSLP |
| DESCRIPTION | Thymic stromal lymphopoietin |
| ALIASES | - |
| NCBI_ENTREZ_NO | 85480 |
| UNIPROT_ACCESS_NO | Q969D9 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Atopic Dermatitis (Adult and Chilhood) |
| SAMPLE | Serum |
| TECHNIQUES | ELISA |
| OMICS | Others |
| STUDY | Low Throughput |
| GEO_PRIDE_ACCESS_NO | NA |
| COMMENTS | Serum TSLP levels were significantly higher in the both adult and childhood Atopic Dermatitis as compared to healthy controls but, no differences were seen in TSLP level between children and adults with Atopic Dermatitis. |
| REFERENCE | 27152943 |
| IMMUNITY_TERM | Yes |
| GO_MOLECULAR_FUNCTION | Cytokine activity, interleukin-7 receptor binding. |
| GO_BIOLOGICAL_PROCESS | Positive regulation of cytokine-mediated signaling pathway, positive regulation of cell proliferation, regulation of signaling receptor activity, positive regulation of chemokine production, positive regulation of interleukin-10 production, positive regulation of interleukin-13 production, positive regulation of interleukin-5 production, positive regulation of interleukin-6 production, positive regulation of mast cell activation, interleukin-7-mediated signaling pathway, positive regulation of tyrosine phosphorylation of STAT protein, negative regulation of apoptotic process, positive regulation of inflammatory response, positive regulation of chemokine (C-C motif) ligand 1 production, positive regulation of granulocyte colony-stimulating factor production, positive regulation of STAT cascade, positive regulation of interleukin-5 secretion. |
| BIOGRID_INTERACTION_ID | 124555 |
| SNP_ID | 300087 300088 300213 300927 300802 300877 301048 301049 300751 300689 |
| DRUG_ID | 4124 |
| STRUCTURE_ID | 202588 |
| MONOCLONAL_ANTIBODY | - |