Record No:1
| ACCESS NO | D102877 |
| GENE_NAME | ORMDL3 |
| DESCRIPTION | ORMDL sphingolipid biosynthesis regulator 3 |
| ALIASES | - |
| NCBI_ENTREZ_NO | 94103 |
| UNIPROT_ACCESS_NO | Q8N138 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma |
| SAMPLE | Bronchial Epithelial Cells (BEC), Broncho Alveolar Lavage (BAL) Cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE67940, GSE43696 |
| COMMENTS | The expression levels of ORMDL3 were higher in severe asthma than controls in BEC. |
| REFERENCE | 27050946 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | Protein binding. |
| GO_BIOLOGICAL_PROCESS | Ceramide metabolic process, neutrophil degranulation, cellular sphingolipid homeostasis, negative regulation of ceramide biosynthetic process. |
| BIOGRID_INTERACTION_ID | 125114 |
| SNP_ID | 300062 300128 300217 300447 300507 300642 301016 301017 301018 301020 300643 300712 |
| DRUG_ID | - |
| STRUCTURE_ID | 203752 |
| MONOCLONAL_ANTIBODY | - |