Record No:1
| ACCESS NO | D103310 |
| GENE_NAME | miR-34 |
| DESCRIPTION | MicroRNA 34A |
| ALIASES | MIRN34A, miRNA34A, mir-34, mir-34a, MIR34A. |
| NCBI_ENTREZ_NO | 407040 |
| UNIPROT_ACCESS_NO | - |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma |
| SAMPLE | CD4 T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | NA |
| COMMENTS | Compared with healthy controls, miR-34 was up regulated in CD4 T cells of Asthma patients. |
| REFERENCE | 30594051 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | mRNA binding involved in posttranscriptional gene silencing. |
| GO_BIOLOGICAL_PROCESS | Cellular response to DNA damage stimulus, positive regulation of gene expression, positive regulation of cardiac muscle cell apoptotic process, positive regulation of cell death, negative regulation of angiogenesis, negative regulation of cell migration, tumor necrosis factor-mediated signaling pathway, gene silencing by miRNA, cholesterol homeostasis, response to axon injury, negative regulation of B cell receptor signaling pathway, positive regulation of smooth muscle cell differentiation, negative regulation of protein kinase B signaling, negative regulation of vascular wound healing, triglyceride homeostasis, positive regulation of cell cycle arrest, cellular response to hypoxia, negative regulation of smooth muscle cell chemotaxis, negative regulation of calcium ion import, positive regulation of blood vessel endothelial cell differentiation, negative regulation of lipid transporter activity, negative regulation of amyloid-beta clearance, positive regulation of protein acetylation, negative regulation of sprouting angiogenesis, negative regulation of vascular smooth muscle cell proliferation, negative regulation of vascular associated smooth muscle cell migration, positive regulation of connective tissue replacement, positive regulation of hydrogen peroxide-induced cell death, negative regulation of vascular endothelial cell proliferation, positive regulation of cellular senescence. |
| BIOGRID_INTERACTION_ID | 135889 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | - |
| MONOCLONAL_ANTIBODY | - |