Record No:1
| ACCESS NO | D103323 |
| GENE_NAME | miR-29b |
| DESCRIPTION | MicroRNA 29B |
| ALIASES | MIRN29B1, miR-29b, miRNA29B1, mir-29b-1, MIR29B1, MIRN29B2, MIR29B2. |
| NCBI_ENTREZ_NO | 407024, 407025 |
| UNIPROT_ACCESS_NO | - |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma |
| SAMPLE | CD4 T cells |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | NA |
| COMMENTS | Compared with healthy controls, miR-29b was down regulated in CD4 T cells of Asthma patients. |
| REFERENCE | 30594051 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | mRNA binding involved in posttranscriptional gene silencing. |
| GO_BIOLOGICAL_PROCESS | Negative regulation of cell proliferation, positive regulation of gene expression, negative regulation of gene expression, negative regulation of epithelial to mesenchymal transition, positive regulation of triglyceride biosynthetic process, positive regulation of cell migration, negative regulation of cell migration, negative regulation of transforming growth factor beta receptor signaling pathway, negative regulation of collagen biosynthetic process, gene silencing by miRNA, miRNA mediated inhibition of translation, positive regulation of apoptotic process, negative regulation of MAPK cascade, regulation of DNA methylation, positive regulation of fat cell differentiation, negative regulation of epithelial cell proliferation, negative regulation of protein secretion, negative regulation of protein kinase B signaling, regulation of blood vessel remodeling, negative regulation of circulating fibrinogen levels, negative regulation of canonical Wnt signaling pathway, negative regulation of extracellular matrix assembly, negative regulation of NIK/NF-kappaB signaling, positive regulation of mitochondrial membrane permeability involved in apoptotic process, negative regulation of mesenchymal stem cell proliferation, negative regulation of oxidative stress-induced cell death, negative regulation of cellular response to transforming growth factor beta stimulus, regulation of aorta morphogenesis, negative regulation of collagen fibril organization, negative regulation of matrix metallopeptidase secretion, positive regulation of metalloendopeptidase activity, regulation of epithelium regeneration, negative regulation of metallopeptidase activity, positive regulation of canonical Wnt signaling pathway involved in osteoblast differentiation, negative regulation of intestinal epithelial cell development, negative regulation of G1/S transition of mitotic cell cycle. |
| BIOGRID_INTERACTION_ID | - |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | - |
| MONOCLONAL_ANTIBODY | - |