Record No:1
ACCESS NO | D104446 |
GENE_NAME | miR-142-3p |
DESCRIPTION | MicroRNA 142 |
ALIASES | MIRN142, mir-142, MIR142. |
NCBI_ENTREZ_NO | 406934 |
UNIPROT_ACCESS_NO | - |
ORGANISM | Human |
DISEASE_PHENOTYPE | Asthma |
SAMPLE | Induced Sputum |
TECHNIQUES | qRT-PCR |
OMICS | Genomics |
STUDY | High Throughput |
GEO_PRIDE_ACCESS_NO | NA |
COMMENTS | miR-142-3p was significantly upregulated in sputum of patients with severe asthma compared with that in healthy control subjects and was highest in patients with neutrophilic asthma. miR-142-3p expression was associated also with airway obstruction (FEV1/forced vital capacity). |
REFERENCE | 27155035 |
IMMUNITY_TERM | Yes |
GO_MOLECULAR_FUNCTION | - |
GO_BIOLOGICAL_PROCESS | Response to lipopolysaccharide, response to tumor necrosis factor, regulation of synaptic transmission (glutamatergic), positive regulation of astrocyte activation, response to interleukin-1, positive regulation of neuroinflammatory response, positive regulation of microglial cell activation. |
BIOGRID_INTERACTION_ID | 135783 |
SNP_ID | - |
DRUG_ID | - |
STRUCTURE_ID | - |
MONOCLONAL_ANTIBODY | - |