Record No:1
| ACCESS NO | D105273 |
| GENE_NAME | PHLDB2 |
| DESCRIPTION | Pleckstrin homology like domain family B member 2 |
| ALIASES | LL5b, LL5beta. |
| NCBI_ENTREZ_NO | 90102 |
| UNIPROT_ACCESS_NO | Q86SQ0 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Severe Asthma |
| SAMPLE | Epithelial Brushings |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE89809 |
| COMMENTS | PHLDB2 was significantly up regulated in epithelial brushings of severe asthmatics as compared to healthy subjects. |
| REFERENCE | 28933920 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | Protein binding, cadherin binding. |
| GO_BIOLOGICAL_PROCESS | Microtubule cytoskeleton organization, regulation of gastrulation, regulation of epithelial to mesenchymal transition, establishment of protein localization, negative regulation of stress fiber assembly, negative regulation of focal adhesion assembly, regulation of microtubule cytoskeleton organization, negative regulation of wound healing (spreading of epidermal cells), positive regulation of basement membrane assembly involved in embryonic body morphogenesis. |
| BIOGRID_INTERACTION_ID | 124661 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 208209 |
| MONOCLONAL_ANTIBODY | - |