Record No:1
| ACCESS NO | D106235 |
| GENE_NAME | miR-146a |
| DESCRIPTION | MicroRNA 146a |
| ALIASES | MIRN146, MIRN146A, MIR146A, miRNA146A. |
| NCBI_ENTREZ_NO | 406938 |
| UNIPROT_ACCESS_NO | - |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Childhood Asthma |
| SAMPLE | Blood Plasma |
| TECHNIQUES | qRT-PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| GEO_PRIDE_ACCESS_NO | NA |
| COMMENTS | miR-146a was upregulated in asthmatic children. miR-146a plays a role in eosinophilic endotypic classification of asthma. miR-146a only correlated to eosinophil percentage. |
| REFERENCE | 29635981 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | mRNA binding involved in posttranscriptional gene silencing. |
| GO_BIOLOGICAL_PROCESS | Negative regulation of endothelial cell proliferation, positive regulation of gene expression, negative regulation of angiogenesis, gene silencing by miRNA, positive regulation of fibroblast growth factor receptor signaling pathway, positive regulation of cell migration involved in sprouting angiogenesis, negative regulation of cell migration involved in sprouting angiogenesis, positive regulation of apoptotic process in bone marrow, positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis, positive regulation of cellular senescence. |
| BIOGRID_INTERACTION_ID | 135787 |
| SNP_ID | 300143 300839 |
| DRUG_ID | - |
| STRUCTURE_ID | - |
| MONOCLONAL_ANTIBODY | - |