Record No:1
| ACCESS NO | D106413 |
| GENE_NAME | SEMA5A |
| DESCRIPTION | Semaphorin 5A |
| ALIASES | SEMAF, semF. |
| NCBI_ENTREZ_NO | 9037 |
| UNIPROT_ACCESS_NO | Q13591 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Childhood Asthma |
| SAMPLE | Peripheral Blood Mononuclear Cells (PBMCs) |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE96783 |
| COMMENTS | SEMA5A was up regulated in asthmatics as compared to healthy controls. |
| REFERENCE | 29518416 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | Protein binding, semaphorin receptor binding, chondroitin sulfate proteoglycan binding, heparan sulfate proteoglycan binding, chemorepellent activity, syndecan binding. |
| GO_BIOLOGICAL_PROCESS | Neural crest cell migration, positive regulation of endothelial cell proliferation, blood vessel endothelial cell proliferation involved in sprouting angiogenesis, cell adhesion, negative regulation of cell adhesion, cell-cell signaling, multicellular organism development, nervous system development, axon guidance, axonal fasciculation, diencephalon development, cell differentiation, positive regulation of cell migration, positive regulation of actin filament depolymerization, positive regulation of angiogenesis, axon extension, positive regulation of axon extension involved in axon guidance, negative regulation of axon extension involved in axon guidance, positive chemotaxis, positive regulation of protein kinase B signaling, cell chemotaxis, semaphorin-plexin signaling pathway, positive regulation of canonical Wnt signaling pathway, neuron projection guidance, signal clustering, negative regulation of endothelial cell apoptotic process, positive regulation of endothelial cell chemotaxis. |
| BIOGRID_INTERACTION_ID | 114501 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 209446 |
| MONOCLONAL_ANTIBODY | - |