Record No:1
| ACCESS NO | D106712 |
| GENE_NAME | SEMA7A |
| DESCRIPTION | Semaphorin 7A (John Milton Hagen blood group) |
| ALIASES | CD108, CDw108, H-SEMA-K1, H-Sema-L, JMH, SEMAK1, SEMAL. |
| NCBI_ENTREZ_NO | 8482 |
| UNIPROT_ACCESS_NO | O75326 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma |
| SAMPLE | Airway Epithelial Brushings |
| TECHNIQUES | RNA Sequencing |
| OMICS | Genomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | NA |
| COMMENTS | SEMA7A was significantly up regulated in asthmatics as compared to control group. |
| REFERENCE | 29064281 |
| IMMUNITY_TERM | Yes |
| GO_MOLECULAR_FUNCTION | Integrin binding, protein binding, semaphorin receptor binding, chemorepellent activity. |
| GO_BIOLOGICAL_PROCESS | Osteoblast differentiation, neural crest cell migration, positive regulation of protein phosphorylation, inflammatory response, immune response, integrin-mediated signaling pathway, multicellular organism development, nervous system development, olfactory lobe development, cell differentiation, positive regulation of cell migration, neuron projection development, positive regulation of axon extension, axon extension, negative regulation of axon extension involved in axon guidance, regulation of inflammatory response, negative chemotaxis, positive regulation of macrophage cytokine production, positive regulation of ERK1 and ERK2 cascade, semaphorin-plexin signaling pathway. |
| BIOGRID_INTERACTION_ID | 114056 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 204434 |
| MONOCLONAL_ANTIBODY | Anti-Semaphorin 7a antibody for Human. |