Record No:1
| ACCESS NO | D106856 |
| GENE_NAME | IFI16 |
| DESCRIPTION | Interferon gamma inducible protein 16 |
| ALIASES | IFNGIP1, PYHIN2. |
| NCBI_ENTREZ_NO | 3428 |
| UNIPROT_ACCESS_NO | Q16666 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma |
| SAMPLE | Whole Blood |
| TECHNIQUES | Microarray, qRT-PCR |
| OMICS | Genomics |
| STUDY | High Throughput, Low Throughput |
| GEO_PRIDE_ACCESS_NO | NA |
| COMMENTS | IFI16 was significantly up regulated in asthmtics as compared to healthy controls. |
| REFERENCE | 29064281 |
| IMMUNITY_TERM | Yes |
| GO_MOLECULAR_FUNCTION | RNA polymerase II proximal promoter sequence-specific DNA binding, DNA-binding transcription repressor activity (RNA polymerase II-specific), DNA binding, double-stranded DNA binding, RNA binding, protein binding, transcription factor binding. |
| GO_BIOLOGICAL_PROCESS | Negative regulation of transcription by RNA polymerase II, positive regulation of cytokine production, activation of innate immune response, immune system process, autophagy, apoptotic process, inflammatory response, regulation of autophagy, myeloid cell differentiation, monocyte differentiation, positive regulation of type I interferon production, positive regulation of interleukin-1 beta production, cellular response to interferon-beta, regulation of gene expression (epigenetic), cellular response to glucose starvation, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, negative regulation of DNA binding, negative regulation of viral genome replication, innate immune response, negative regulation of innate immune response, negative regulation of transcription, DNA-templated, positive regulation of transcription by RNA polymerase II, defense response to virus, cellular response to ionizing radiation, intrinsic apoptotic signaling pathway by p53 class mediator, activation of cysteine-type endopeptidase activity, negative regulation of cysteine-type endopeptidase activity. |
| BIOGRID_INTERACTION_ID | 109654 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 208678 208679 |
| MONOCLONAL_ANTIBODY | Anti-IFI16 antibody for Human. |