Record No:1
| ACCESS NO | D107245 |
| GENE_NAME | miR-10a-5p |
| DESCRIPTION | MicroRNA 10a |
| ALIASES | MIRN10A, hsa-mir-10a, miRNA10A, mir-10a. |
| NCBI_ENTREZ_NO | 406902 |
| UNIPROT_ACCESS_NO | - |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, COPD |
| SAMPLE | Primary Bronchial Epithelial Cells (BECs), Serum |
| TECHNIQUES | Next Generation Sequencing, qRT-PCR, Microarray Data Analysis |
| OMICS | Genomics, Bioinformatics |
| STUDY | High Throughput, Low Throughput, High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE25230, GSE38974, GSE67940, GSE41861, GSE63142, GSE43696, GSE4302, GSE20257 |
| COMMENTS | Increased miR-10a-5p level was noted in primary bronchial epithelial cells and serum of patients with asthma and COPD as compared with normal control subjects. |
| REFERENCE | 30696075 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | mRNA binding involved in posttranscriptional gene silencing. |
| GO_BIOLOGICAL_PROCESS | Negative regulation of angiogenesis, positive regulation of vascular endothelial growth factor receptor signaling pathway, gene silencing by miRNA, negative regulation of blood vessel endothelial cell migration, positive regulation of cell migration involved in sprouting angiogenesis, negative regulation of cardiac muscle myoblast proliferation, negative regulation of blood vessel endothelial cell differentiation, negative regulation of cell cycle G1/S phase transition, positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis, negative regulation of cell proliferation in bone marrow, positive regulation of cellular senescence. |
| BIOGRID_INTERACTION_ID | 135751 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | - |
| MONOCLONAL_ANTIBODY | - |