Record No:1
| ACCESS NO | D107246 |
| GENE_NAME | miR-146a-5p |
| DESCRIPTION | MicroRNA 146a |
| ALIASES | MIRN146, MIRN146A, MIR146A, miRNA146A, miR-146a. |
| NCBI_ENTREZ_NO | 406938 |
| UNIPROT_ACCESS_NO | - |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, COPD |
| SAMPLE | Primary Bronchial Epithelial Cells (BECs), Serum |
| TECHNIQUES | Next Generation Sequencing, qRT-PCR, Microarray Data Analysis |
| OMICS | Genomics, Bioinformatics |
| STUDY | High Throughput, Low Throughput, High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE25230, GSE38974, GSE67940, GSE41861, GSE63142, GSE43696, GSE4302, GSE20257 |
| COMMENTS | Increased miR-146a-5p level was noted in primary bronchial epithelial cells and serum of patients with asthma and COPD as compared with normal control subjects. |
| REFERENCE | 30696075 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | mRNA binding involved in posttranscriptional gene silencing. |
| GO_BIOLOGICAL_PROCESS | Negative regulation of endothelial cell proliferation, positive regulation of gene expression, negative regulation of angiogenesis, gene silencing by miRNA, positive regulation of fibroblast growth factor receptor signaling pathway, positive regulation of cell migration involved in sprouting angiogenesis, negative regulation of cell migration involved in sprouting angiogenesis, positive regulation of apoptotic process in bone marrow, positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis, positive regulation of cellular senescence. |
| BIOGRID_INTERACTION_ID | 135787 |
| SNP_ID | 300143 300839 |
| DRUG_ID | - |
| STRUCTURE_ID | - |
| MONOCLONAL_ANTIBODY | - |