Record No:1


ACCESS NOD107532
GENE_NAMERPS6KB1
DESCRIPTIONRibosomal protein S6 kinase B1
ALIASESPS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha.
NCBI_ENTREZ_NO6198
UNIPROT_ACCESS_NOP23443
ORGANISMHuman
DISEASE_PHENOTYPEEosinophilic Asthma, Neutrophilic Asthma
SAMPLEPeripheral Blood
TECHNIQUESMicroarray
OMICSGenomics
STUDYHigh Throughput
GEO_PRIDE_ACCESS_NOGSE106230, GSE117038
COMMENTSRPS6KB1 was significantly up regulated in eosinophilic asthma as compared to neutrophilic asthma group.
REFERENCE30941157
IMMUNITY_TERMNo
GO_MOLECULAR_FUNCTIONNucleotide binding, protein kinase activity, protein serine/threonine kinase activity, ribosomal protein S6 kinase activity, protein serine/threonine/tyrosine kinase activity, protein binding, ATP binding, kinase activity, transferase activity.
GO_BIOLOGICAL_PROCESSG1/S transition of mitotic cell cycle, regulation of translation, protein phosphorylation, apoptotic process, cell cycle, signal transduction, phosphorylation, peptidyl-serine phosphorylation, response to nutrient levels, TOR signaling, cellular response to insulin stimulus, intracellular signal transduction, negative regulation of apoptotic process, long-chain fatty acid import, positive regulation of translation, positive regulation of mitotic cell cycle, positive regulation of translational initiation, negative regulation of insulin receptor signaling pathway, phosphatidylinositol-mediated signaling, cellular response to growth factor stimulus.
BIOGRID_INTERACTION_ID112112
SNP_ID-
DRUG_ID-
STRUCTURE_ID208028
208029
208030
208031
208032
208033
MONOCLONAL_ANTIBODYAnti-S6K1 antibody for Mouse, Rat, Human.