Record No:1
ACCESS NO | D107532 |
GENE_NAME | RPS6KB1 |
DESCRIPTION | Ribosomal protein S6 kinase B1 |
ALIASES | PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha. |
NCBI_ENTREZ_NO | 6198 |
UNIPROT_ACCESS_NO | P23443 |
ORGANISM | Human |
DISEASE_PHENOTYPE | Eosinophilic Asthma, Neutrophilic Asthma |
SAMPLE | Peripheral Blood |
TECHNIQUES | Microarray |
OMICS | Genomics |
STUDY | High Throughput |
GEO_PRIDE_ACCESS_NO | GSE106230, GSE117038 |
COMMENTS | RPS6KB1 was significantly up regulated in eosinophilic asthma as compared to neutrophilic asthma group. |
REFERENCE | 30941157 |
IMMUNITY_TERM | No |
GO_MOLECULAR_FUNCTION | Nucleotide binding, protein kinase activity, protein serine/threonine kinase activity, ribosomal protein S6 kinase activity, protein serine/threonine/tyrosine kinase activity, protein binding, ATP binding, kinase activity, transferase activity. |
GO_BIOLOGICAL_PROCESS | G1/S transition of mitotic cell cycle, regulation of translation, protein phosphorylation, apoptotic process, cell cycle, signal transduction, phosphorylation, peptidyl-serine phosphorylation, response to nutrient levels, TOR signaling, cellular response to insulin stimulus, intracellular signal transduction, negative regulation of apoptotic process, long-chain fatty acid import, positive regulation of translation, positive regulation of mitotic cell cycle, positive regulation of translational initiation, negative regulation of insulin receptor signaling pathway, phosphatidylinositol-mediated signaling, cellular response to growth factor stimulus. |
BIOGRID_INTERACTION_ID | 112112 |
SNP_ID | - |
DRUG_ID | - |
STRUCTURE_ID | 208028 208029 208030 208031 208032 208033 |
MONOCLONAL_ANTIBODY | Anti-S6K1 antibody for Mouse, Rat, Human. |