Record No:1
| ACCESS NO | D107532 |
| GENE_NAME | RPS6KB1 |
| DESCRIPTION | Ribosomal protein S6 kinase B1 |
| ALIASES | PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha. |
| NCBI_ENTREZ_NO | 6198 |
| UNIPROT_ACCESS_NO | P23443 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Eosinophilic Asthma, Neutrophilic Asthma |
| SAMPLE | Peripheral Blood |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE106230, GSE117038 |
| COMMENTS | RPS6KB1 was significantly up regulated in eosinophilic asthma as compared to neutrophilic asthma group. |
| REFERENCE | 30941157 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | Nucleotide binding, protein kinase activity, protein serine/threonine kinase activity, ribosomal protein S6 kinase activity, protein serine/threonine/tyrosine kinase activity, protein binding, ATP binding, kinase activity, transferase activity. |
| GO_BIOLOGICAL_PROCESS | G1/S transition of mitotic cell cycle, regulation of translation, protein phosphorylation, apoptotic process, cell cycle, signal transduction, phosphorylation, peptidyl-serine phosphorylation, response to nutrient levels, TOR signaling, cellular response to insulin stimulus, intracellular signal transduction, negative regulation of apoptotic process, long-chain fatty acid import, positive regulation of translation, positive regulation of mitotic cell cycle, positive regulation of translational initiation, negative regulation of insulin receptor signaling pathway, phosphatidylinositol-mediated signaling, cellular response to growth factor stimulus. |
| BIOGRID_INTERACTION_ID | 112112 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 208028 208029 208030 208031 208032 208033 |
| MONOCLONAL_ANTIBODY | Anti-S6K1 antibody for Mouse, Rat, Human. |