Record No:1
| ACCESS NO | D107553 |
| GENE_NAME | miR-98-5p |
| DESCRIPTION | MicroRNA 98 |
| ALIASES | MIRLET7L, MIRN98, hsa-mir-98, miR-98, MIR98. |
| NCBI_ENTREZ_NO | 407054 |
| UNIPROT_ACCESS_NO | - |
| ORGANISM | Human (Children) |
| DISEASE_PHENOTYPE | Bronchial Asthma |
| SAMPLE | Serum |
| TECHNIQUES | qRT-PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| GEO_PRIDE_ACCESS_NO | NA |
| COMMENTS | The current study showed that the relative expression level of miR-98-5p in the asthmatic remission group and asthmatic acute group was significantly lower than that in the healthy control group, and the relative expression level of miR-98-5p in the asthmatic acute group was significantly lower than that in the asthmatic remission group. The current study suggests that miR-98-5p may affect the occurrence and development of bronchial asthma in children via affecting the expression of IL13. |
| REFERENCE | 30868866 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | mRNA binding involved in posttranscriptional gene silencing. |
| GO_BIOLOGICAL_PROCESS | Negative regulation of extracellular matrix disassembly, gene silencing by miRNA, miRNA mediated inhibition of translation, positive regulation of neuron apoptotic process, negative regulation of interleukin-6-mediated signaling pathway, cellular response to amyloid-beta, negative regulation of vascular endothelial cell proliferation. |
| BIOGRID_INTERACTION_ID | 135903 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | - |
| MONOCLONAL_ANTIBODY | - |