Record No:1
| ACCESS NO | D107739 |
| GENE_NAME | BCL11B |
| DESCRIPTION | BAF chromatin remodeling complex subunit BCL11B |
| ALIASES | ATL1, ATL1-alpha, ATL1-beta, ATL1-delta, ATL1-gamma, CTIP-2, CTIP2, IDDFSTA, IMD49, RIT1, ZNF856B, hRIT1-alpha. |
| NCBI_ENTREZ_NO | 64919 |
| UNIPROT_ACCESS_NO | Q9C0K0 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma |
| SAMPLE | CD4 T cells |
| TECHNIQUES | qRT-PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| GEO_PRIDE_ACCESS_NO | NA |
| COMMENTS | Decreased expression of BCL11B was noted in CD4 Tcells from asthma patients as compared to control group. |
| REFERENCE | 30088373 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | RNA polymerase II proximal promoter sequence-specific DNA binding, DNA-binding transcription factor activity (RNA polymerase II-specific), DNA-binding transcription activator activity (RNA polymerase II-specific), nucleic acid binding, DNA-binding transcription factor activity, protein binding, sequence-specific DNA binding, metal ion binding. |
| GO_BIOLOGICAL_PROCESS | Keratinocyte development, epithelial cell morphogenesis, regulation of DNA-templated transcription, axonogenesis, negative regulation of cell proliferation, post-embryonic development, regulation of gene expression, regulation of keratinocyte proliferation, regulation of lipid metabolic process, striatal medium spiny neuron differentiation, commitment of neuronal cell to specific neuron type in forebrain, central nervous system neuron differentiation, post-embryonic camera-type eye development, T cell differentiation in thymus, T cell receptor V(D)J recombination, hematopoietic stem cell migration, odontogenesis of dentin-containing tooth, negative regulation of apoptotic process, positive T cell selection, skin development, regulation of neuron differentiation, positive regulation of transcription by RNA polymerase II, alpha-beta T cell differentiation, thymus development, olfactory bulb axon guidance, lymphoid lineage cell migration into thymus. |
| BIOGRID_INTERACTION_ID | 122343 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 205681 |
| MONOCLONAL_ANTIBODY | Anti-Ctip2 antibody for Mouse, Rat, Guinea pig, Human, Zebrafish, Cynomolgus monkey. |