Record No:1
| ACCESS NO | D107993 |
| GENE_NAME | miR-199a-5p |
| DESCRIPTION | MicroRNA 199a |
| ALIASES | MIR-199-s, MIRN199A1, mir-199a-1, MIR199A1, MIR-199-s, MIRN199A2, mir-199a-2, MIR199A2. |
| NCBI_ENTREZ_NO | 406976, 406977 |
| UNIPROT_ACCESS_NO | - |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma |
| SAMPLE | Blood Plasma, Induced Sputum |
| TECHNIQUES | qRT-PCR |
| OMICS | Genomics |
| STUDY | Low Throughput |
| GEO_PRIDE_ACCESS_NO | NA |
| COMMENTS | The miRNA-199a-5p levels in plasma and sputum were increased significantly in patients with neutrophilic asthma compared to healthy subjects. Plasma miR-199a-5p was negatively correlated with pulmonary function. |
| REFERENCE | 29505605 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | mRNA binding involved in posttranscriptional gene silencing. |
| GO_BIOLOGICAL_PROCESS | Re-entry into mitotic cell cycle, negative regulation of receptor internalization, positive regulation of cytosolic calcium ion concentration, negative regulation of autophagy, positive regulation of endothelial cell migration, negative regulation of cardiac muscle cell apoptotic process, negative regulation of low-density lipoprotein particle clearance, positive regulation of TOR signaling, gene silencing by miRNA, negative regulation of nitric oxide biosynthetic process, NOT regulation of angiogenesis, positive regulation of angiogenesis, positive regulation of protein kinase B signaling, NOT regulation of cardiac muscle cell proliferation, negative regulation of cardiac muscle cell proliferation, positive regulation of cardiac muscle cell proliferation, cell growth involved in cardiac muscle cell development, positive regulation of cell growth involved in cardiac muscle cell development, negative regulation of cell growth involved in cardiac muscle cell development, positive regulation of lung blood pressure, positive regulation of cardiac muscle hypertrophy in response to stress, positive regulation of cardiac muscle tissue regeneration, NOT regulation of connective tissue replacement, positive regulation of connective tissue replacement. |
| BIOGRID_INTERACTION_ID | 135825, 135826 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | - |
| MONOCLONAL_ANTIBODY | - |