Record No:1
| ACCESS NO | D109366 |
| GENE_NAME | TBL1XR1 |
| DESCRIPTION | TBL1X receptor 1 |
| ALIASES | C21, DC42, IRA1, MRD41, TBLR1. |
| NCBI_ENTREZ_NO | 79718 |
| UNIPROT_ACCESS_NO | Q9BZK7 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | TBL1XR1 was increased in asthmatic subjects as compared to that of allergic rhinitis and healthy controls. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | DNA binding, transcription corepressor activity, protein binding, beta-catenin binding, histone binding, transcription regulatory region DNA binding, protein N-terminus binding. |
| GO_BIOLOGICAL_PROCESS | Negative regulation of transcription by RNA polymerase II, blastocyst hatching, response to dietary excess, chromatin organization, regulation of transcription by RNA polymerase II, regulation of gene expression, lipid catabolic process, histone deacetylation, regulation of lipid metabolic process, multicellular organism growth, proteasome-mediated ubiquitin-dependent protein catabolic process, negative regulation of DNA-templated transcription, positive regulation of DNA-templated transcription, positive regulation of transcription by RNA polymerase II, white fat cell differentiation, adipose tissue development, fat pad development, regulation of triglyceride metabolic process, positive regulation of canonical Wnt signaling pathway. |
| BIOGRID_INTERACTION_ID | 122834 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 205862 |
| MONOCLONAL_ANTIBODY | Anti-TBLR1/TBL1XR1 antibody for Human, Mouse, Rat. |