Record No:1
| ACCESS NO | D109376 |
| GENE_NAME | SGK1 |
| DESCRIPTION | Serum/glucocorticoid regulated kinase 1 |
| ALIASES | SGK. |
| NCBI_ENTREZ_NO | 6446 |
| UNIPROT_ACCESS_NO | O00141 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | SGK1 was decreased in asthmatic patients as compared to allergic rhinitis patients and healthy controls. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | Protein kinase activity, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, calcium channel regulator activity, protein binding, ATP binding, potassium channel regulator activity, kinase activity, transferase activity, sodium channel regulator activity, chloride channel regulator activity, phosphatidylinositol binding. |
| GO_BIOLOGICAL_PROCESS | Regulation of cell growth, protein phosphorylation, sodium ion transport, apoptotic process, cellular response to DNA damage stimulus, long-term memory, regulation of blood pressure, phosphorylation, peptidyl-serine phosphorylation, regulation of cell migration, positive regulation of transporter activity, ion transmembrane transport, intracellular signal transduction, regulation of cell proliferation, regulation of apoptotic process, neuron projection morphogenesis, regulation of catalytic activity, regulation of DNA-binding transcription factor activity, regulation of gastric acid secretion, renal sodium ion absorption. |
| BIOGRID_INTERACTION_ID | 112344 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 204370 |
| MONOCLONAL_ANTIBODY | Anti-SGK1 antibody for Human, Rat, Mouse. |