Record No:1
| ACCESS NO | D109399 |
| GENE_NAME | DYRK3 |
| DESCRIPTION | Dual specificity tyrosine phosphorylation regulated kinase 3 |
| ALIASES | DYRK5, RED, REDK, hYAK3-2. |
| NCBI_ENTREZ_NO | 8444 |
| UNIPROT_ACCESS_NO | O43781 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | DYRK3 was significantly decreased in asthmatics as compared to healthy subjects. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | Magnesium ion binding, protein kinase activity, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity, ATP binding, kinase activity, transferase activity, metal ion binding. |
| GO_BIOLOGICAL_PROCESS | Protein phosphorylation, cell cycle, phosphorylation, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, peptidyl-tyrosine phosphorylation, erythrocyte differentiation, nuclear speck organization, stress granule disassembly, negative regulation of apoptotic process, negative regulation of DNA damage response (signal transduction by p53 class mediator), cell division, regulation of cellular response to stress, positive regulation of cell cycle G2/M phase transition, organelle disassembly, regulation of TORC1 signaling. |
| BIOGRID_INTERACTION_ID | 114022 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 206859 |
| MONOCLONAL_ANTIBODY | - |