Record No:1
| ACCESS NO | D109426 |
| GENE_NAME | AREG |
| DESCRIPTION | Amphiregulin |
| ALIASES | ARB, CRDGF, SDGF. |
| NCBI_ENTREZ_NO | 374 |
| UNIPROT_ACCESS_NO | P15514 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | AREG was significantly decreased in asthmatics as compared to healthy subjects. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | Yes |
| GO_MOLECULAR_FUNCTION | Cytokine activity, epidermal growth factor receptor binding, protein binding, growth factor activity. |
| GO_BIOLOGICAL_PROCESS | ER to Golgi vesicle-mediated transport, epidermal growth factor receptor signaling pathway, G-protein coupled receptor signaling pathway, cell-cell signaling, cell proliferation, positive regulation of cell proliferation, regulation of signaling receptor activity, glial cell proliferation, response to organic cyclic compound, neuron projection development, response to estradiol, positive regulation of phosphorylation, response to hydrogen peroxide, response to peptide hormone, negative regulation of osteoblast differentiation, positive regulation of DNA replication, COPII vesicle coating, positive regulation of peptidyl-tyrosine phosphorylation, response to glucocorticoid, response to cAMP, dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis, mammary gland branching involved in thelarche, mammary gland alveolus development, epithelial cell proliferation involved in mammary gland duct elongation. |
| BIOGRID_INTERACTION_ID | 106869 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 200226 |
| MONOCLONAL_ANTIBODY | Anti-Amphiregulin antibody for Human, Mouse. |