Record No:1
| ACCESS NO | D109435 |
| GENE_NAME | FOSL2 |
| DESCRIPTION | FOS like 2, AP-1 transcription factor subunit |
| ALIASES | FRA2. |
| NCBI_ENTREZ_NO | 2355 |
| UNIPROT_ACCESS_NO | P15408 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | FOSL2 was significantly decreased in asthmatics as compared to healthy subjects. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | RNA polymerase II regulatory region sequence-specific DNA binding, RNA polymerase II proximal promoter sequence-specific DNA binding, DNA-binding transcription factor activity (RNA polymerase II-specific), DNA-binding transcription activator activity (RNA polymerase II-specific), DNA binding, chromatin binding, DNA-binding transcription factor activity, protein binding. |
| GO_BIOLOGICAL_PROCESS | Keratinocyte development, regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II, cell death, positive regulation of DNA-templated transcription, positive regulation of transcription by RNA polymerase II, positive regulation of fibroblast proliferation. |
| BIOGRID_INTERACTION_ID | 108638 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 204453 |
| MONOCLONAL_ANTIBODY | Anti-FRA2 antibody for Human, Mouse, Rat. |