Record No:1
| ACCESS NO | D109445 |
| GENE_NAME | DTL |
| DESCRIPTION | Denticleless E3 ubiquitin protein ligase homolog |
| ALIASES | CDT2, DCAF2, L2DTL, RAMP. |
| NCBI_ENTREZ_NO | 51514 |
| UNIPROT_ACCESS_NO | Q9NZJ0 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | DTL was significantly decreased in asthmatics as compared to healthy subjects. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | Contributes to ubiquitin-protein transferase activity, protein binding. |
| GO_BIOLOGICAL_PROCESS | Protein polyubiquitination, DNA replication, ubiquitin-dependent protein catabolic process, protein monoubiquitination, cellular response to DNA damage stimulus, response to UV, positive regulation of G2/M transition of mitotic cell cycle, protein ubiquitination, translesion synthesis, DNA damage response (detection of DNA damage), post-translational protein modification, positive regulation of protein catabolic process, rhythmic process, regulation of cell cycle, signal transduction involved in G2 DNA damage checkpoint. |
| BIOGRID_INTERACTION_ID | 119582 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 207494 |
| MONOCLONAL_ANTIBODY | Anti-CDT2/RAMP antibody for Human, Mouse, Rat. |