Record No:1
| ACCESS NO | D109449 |
| GENE_NAME | FSCN1 |
| DESCRIPTION | Fascin actin-bundling protein 1 |
| ALIASES | FAN1, HSN, SNL, p55. |
| NCBI_ENTREZ_NO | 6624 |
| UNIPROT_ACCESS_NO | Q16658 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | FSCN1 was significantly decreased in asthmatics as compared to healthy subjects. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | Yes |
| GO_MOLECULAR_FUNCTION | RNA binding, actin binding, protein binding, drug binding, protein binding, bridging, cadherin binding, actin filament binding. |
| GO_BIOLOGICAL_PROCESS | Actin filament organization, cell-cell junction assembly, establishment or maintenance of cell polarity, cell proliferation, anatomical structure morphogenesis, positive regulation of lamellipodium assembly, cell migration, cytokine-mediated signaling pathway, microspike assembly, actin cytoskeleton organization, regulation of microvillus assembly, regulation of actin cytoskeleton organization, establishment of apical/basal cell polarity, cell motility, actin filament bundle assembly, positive regulation of filopodium assembly, positive regulation of podosome assembly, positive regulation of extracellular matrix disassembly. |
| BIOGRID_INTERACTION_ID | 112508 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 201884 201885 201886 |
| MONOCLONAL_ANTIBODY | Anti-Fascin antibody for Human, Rat, Mouse. |