Record No:1


ACCESS NOD109451
GENE_NAMEPER1
DESCRIPTIONPeriod circadian regulator 1
ALIASESPER, RIGUI, hPER.
NCBI_ENTREZ_NO5187
UNIPROT_ACCESS_NOO15534
ORGANISMHuman
DISEASE_PHENOTYPEAsthma, Allergic Rhinitis
SAMPLECD4 T cells
TECHNIQUESRNA Sequencing
OMICSTranscriptomics
STUDYHigh Throughput
GEO_PRIDE_ACCESS_NOGSE75011
COMMENTSPER1 was significantly decreased in asthmatics as compared to allergic rhinitis patients and healthy subjects.
REFERENCE27271570
IMMUNITY_TERMNo
GO_MOLECULAR_FUNCTIONTranscription regulatory region sequence-specific DNA binding, RNA polymerase II proximal promoter sequence-specific DNA binding, transcription factor activity ( transcription factor binding), transcription corepressor binding, protein binding, transcription factor binding, kinase binding, chromatin DNA binding, ubiquitin protein ligase binding, E-box binding.
GO_BIOLOGICAL_PROCESSNegative regulation of transcription by RNA polymerase II, regulation of sodium ion transport, DNA-templated transcription, regulation of DNA-templated transcription, circadian rhythm, response to light stimulus, entrainment of circadian clock, posttranscriptional regulation of gene expression, circadian regulation of gene expression, regulation of hair cycle, regulation of circadian rhythm, negative regulation of I-kappaB kinase/NF-kappaB signaling, entrainment of circadian clock by photoperiod, histone H3 acetylation, histone H4 acetylation, negative regulation of DNA-templated transcription, positive regulation of transcription by RNA polymerase II, negative regulation of JNK cascade, rhythmic process, response to cAMP, histone H3 deacetylation, circadian regulation of translation, regulation of cytokine production involved in inflammatory response, regulation of p38MAPK cascade, negative regulation of glucocorticoid receptor signaling pathway.
BIOGRID_INTERACTION_ID111210
SNP_ID-
DRUG_ID-
STRUCTURE_ID200888
MONOCLONAL_ANTIBODY-