Record No:1
| ACCESS NO | D109459 |
| GENE_NAME | RRM2 |
| DESCRIPTION | Ribonucleotide reductase regulatory subunit M2 |
| ALIASES | R2, RR2, RR2M. |
| NCBI_ENTREZ_NO | 6241 |
| UNIPROT_ACCESS_NO | P31350 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | RRM2 was significantly decreased in asthmatics as compared to healthy subjects. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | Ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor, protein binding, oxidoreductase activity, metal ion binding. |
| GO_BIOLOGICAL_PROCESS | Regulation of transcription involved in G1/S transition of mitotic cell cycle, DNA replication, deoxyribonucleotide biosynthetic process, nucleobase-containing small molecule interconversion, oxidation-reduction process, negative regulation of G0 to G1 transition. |
| BIOGRID_INTERACTION_ID | 112155 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 200118 200119 |
| MONOCLONAL_ANTIBODY | Anti-RRM2 antibody for Human; Anti-p53R2 + RRM2 antibody for Human, Rat, Mouse. |