Record No:1
| ACCESS NO | D109462 |
| GENE_NAME | ETV3 |
| DESCRIPTION | ETS variant transcription factor 3 |
| ALIASES | METS, PE-1, PE1. |
| NCBI_ENTREZ_NO | 2117 |
| UNIPROT_ACCESS_NO | P41162 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | ETV3 was significantly decreased in asthmatics as compared to healthy subjects. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | RNA polymerase II regulatory region sequence-specific DNA binding, DNA-binding transcription factor activity (RNA polymerase II-specific), DNA-binding transcription repressor activity (RNA polymerase II-specific), molecular_function, DNA binding, DNA-binding transcription factor activity, DEAD/H-box RNA helicase binding, sequence-specific DNA binding. |
| GO_BIOLOGICAL_PROCESS | Negative regulation of transcription by RNA polymerase II, regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II, biological process, negative regulation of cell proliferation, cell differentiation, cellular response to granulocyte macrophage colony-stimulating factor stimulus. |
| BIOGRID_INTERACTION_ID | 108418 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 207486 |
| MONOCLONAL_ANTIBODY | Anti-ETV3 antibody for Mouse, Rat, Human. |