Record No:1
| ACCESS NO | D109543 |
| GENE_NAME | HIST1H1B |
| DESCRIPTION | H1.5 linker histone, cluster member |
| ALIASES | H1, H1.5, H1B, H1F5, H1s-3, H1-5. |
| NCBI_ENTREZ_NO | 3009 |
| UNIPROT_ACCESS_NO | P16401 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | HIST1H1B was significantly decreased in asthmatics as compared to healthy subjects. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | DNA binding, double-stranded DNA binding, RNA binding, protein binding, chromatin DNA binding, nucleosomal DNA binding. |
| GO_BIOLOGICAL_PROCESS | Negative regulation of transcription by RNA polymerase II, chromatin organization, nucleosome assembly, regulation of DNA-templated transcription, muscle organ development, nucleosome positioning, chromosome condensation, positive regulation of cell growth, negative regulation of chromatin silencing, negative regulation of DNA recombination, protein stabilization, positive regulation of histone H3-K9 methylation, establishment of protein localization to chromatin. |
| BIOGRID_INTERACTION_ID | 109264 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 207688 |
| MONOCLONAL_ANTIBODY | Anti-Histone H1 antibody for Rat, Human. |