Record No:1
| ACCESS NO | D109555 |
| GENE_NAME | CASP9 |
| DESCRIPTION | Caspase 9 |
| ALIASES | APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56. |
| NCBI_ENTREZ_NO | 842 |
| UNIPROT_ACCESS_NO | P55211 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | CASP9 was significantly decreased in asthmatics as compared to healthy subjects. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | Cysteine-type endopeptidase activity, protein binding, enzyme activator activity, peptidase activity, cysteine-type peptidase activity, hydrolase activity, SH3 domain binding, protein kinase binding, cysteine-type endopeptidase activity involved in apoptotic process, cysteine-type endopeptidase activity involved in apoptotic signaling pathway. |
| GO_BIOLOGICAL_PROCESS | Kidney development, response to ischemia, proteolysis, apoptotic process, activation of cysteine-type endopeptidase activity involved in apoptotic process, cellular response to DNA damage stimulus, aging, intrinsic apoptotic signaling pathway in response to DNA damage, activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c, response to UV, response to organic cyclic compound, platelet formation, response to cobalt ion, response to estradiol, response to lipopolysaccharide, glial cell apoptotic process, cellular response to UV, signal transduction in response to DNA damage, regulation of apoptotic process, positive regulation of apoptotic process, positive regulation of neuron apoptotic process, response to antibiotic, cellular response to organic cyclic compound, cellular response to dexamethasone stimulus, leukocyte apoptotic process, extrinsic apoptotic signaling pathway in absence of ligand, regulation of response to DNA damage stimulus. |
| BIOGRID_INTERACTION_ID | 107292 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 205762 205763 205764 205765 |
| MONOCLONAL_ANTIBODY | Anti-Caspase-9 antibody for Human, Mouse, Rat, Monkey. |