Record No:1
| ACCESS NO | D109569 |
| GENE_NAME | GLUL |
| DESCRIPTION | Glutamate-ammonia ligase |
| ALIASES | GLNS, GS, PIG43, PIG59. |
| NCBI_ENTREZ_NO | 2752 |
| UNIPROT_ACCESS_NO | P15104 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | GLUL was significantly decreased in asthmatics as compared to healthy subjects. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | Magnesium ion binding, catalytic activity, glutamate-ammonia ligase activity, protein binding, ATP binding, glutamate binding, transferase activity, ligase activity, protein-cysteine S-palmitoyltransferase activity, manganese ion binding, identical protein binding, dynein light chain binding, metal ion binding. |
| GO_BIOLOGICAL_PROCESS | Neurotransmitter uptake, angiogenesis, glutamate metabolic process, glutamate catabolic process, glutamine biosynthetic process, nitrogen compound metabolic process, cell proliferation, cellular amino acid biosynthetic process, cellular response to starvation, response to glucose, regulation of endothelial cell migration, protein palmitoylation, ammonia assimilation cycle, positive regulation of insulin secretion, ribosome biogenesis, positive regulation of epithelial cell proliferation, protein homooligomerization, positive regulation of synaptic transmission (glutamatergic), regulation of sprouting angiogenesis, regulation of protein localization to nucleolus. |
| BIOGRID_INTERACTION_ID | 109014 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 207696 |
| MONOCLONAL_ANTIBODY | Anti-Glutamine Synthetase antibody for Human, Mouse, Rat, Drosophila melanogaster, Zebrafish, Apteronotus leptorhynchus. |