Record No:1
| ACCESS NO | D109574 |
| GENE_NAME | LFNG |
| DESCRIPTION | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| ALIASES | SCDO3. |
| NCBI_ENTREZ_NO | 3955 |
| UNIPROT_ACCESS_NO | Q8NES3 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | LFNG was significantly decreased in asthmatics as compared to healthy subjects. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | Molecular function, transferase activity, transferase activity, transferring glycosyl groups, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity, metal ion binding. |
| GO_BIOLOGICAL_PROCESS | Ovarian follicle development, somitogenesis, marginal zone B cell differentiation, multicellular organism development, compartment pattern specification, pattern specification process, regulation of Notch signaling pathway, animal organ morphogenesis, regulation of somitogenesis, T cell differentiation, positive regulation of protein binding, protein O-linked fucosylation, positive regulation of Notch signaling pathway, positive regulation of meiotic cell cycle, negative regulation of Notch signaling pathway involved in somitogenesis. |
| BIOGRID_INTERACTION_ID | 110146 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 207691 |
| MONOCLONAL_ANTIBODY | Anti-Lunatic Fringe antibody for Human, Mouse, Rat. |