Record No:1


ACCESS NOD109577
GENE_NAMEKLF2
DESCRIPTIONKruppel like factor 2
ALIASESLKLF.
NCBI_ENTREZ_NO10365
UNIPROT_ACCESS_NOQ9Y5W3
ORGANISMHuman
DISEASE_PHENOTYPEAsthma, Allergic Rhinitis
SAMPLECD4 T cells
TECHNIQUESRNA Sequencing
OMICSTranscriptomics
STUDYHigh Throughput
GEO_PRIDE_ACCESS_NOGSE75011
COMMENTSKLF2 was significantly decreased in asthmatics as compared to healthy subjects.
REFERENCE27271570
IMMUNITY_TERMNo
GO_MOLECULAR_FUNCTIONDNA-binding transcription factor activity (RNA polymerase II-specific), nucleic acid binding, DNA binding, DNA-binding transcription factor activity, protein binding, metal ion binding.
GO_BIOLOGICAL_PROCESSNegative regulation of transcription by RNA polymerase II, cell morphogenesis, in utero embryonic development, regulation of transcription by RNA polymerase II, negative regulation of interleukin-6 production, erythrocyte homeostasis, response to laminar fluid shear stress, multicellular organism growth, positive regulation of transcription from RNA polymerase II promoter in response to stress, regulation of gene expression (epigenetic), erythrocyte maturation, positive regulation of nitric oxide biosynthetic process, positive regulation of DNA-templated transcription, positive regulation of transcription by RNA polymerase II, positive regulation of protein metabolic process, type I pneumocyte differentiation, cellular response to hydrogen peroxide, cellular response to interleukin-1, cellular response to tumor necrosis factor, cellular response to organic cyclic compound, cellular response to cycloheximide, cellular response to fluid shear stress, cellular response to laminar fluid shear stress, cellular stress response to acid chemical, cellular response to peptide, negative regulation of sprouting angiogenesis.
BIOGRID_INTERACTION_ID115645
SNP_ID-
DRUG_ID-
STRUCTURE_ID206359
MONOCLONAL_ANTIBODYAnti-KLF2 antibody for Human.

© Bose Institute, Kolkata, 2020. For any queries regarding DAAB (Version: 2), contact Dr. Sudipto Saha at  ssaha4@jcbose.ac.in