Record No:1
| ACCESS NO | D109581 |
| GENE_NAME | BTG2 |
| DESCRIPTION | BTG family-member 2 |
| ALIASES | APRO1, PC3, TIS21. |
| NCBI_ENTREZ_NO | 7832 |
| UNIPROT_ACCESS_NO | P78543 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | BTG2 was significantly decreased in asthmatics as compared to healthy subjects. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | Transcriptional repressor activity (RNA polymerase II proximal promoter sequence-specific DNA binding), protein binding. |
| GO_BIOLOGICAL_PROCESS | Negative regulation of transcription by RNA polymerase II, DNA repair, DNA-templated transcription, regulation of DNA-templated transcription, protein methylation, cellular response to DNA damage stimulus, DNA damage response (signal transduction by p53 class mediator resulting in cell cycle arrest), negative regulation of cell proliferation, associative learning, response to mechanical stimulus, anterior/posterior pattern specification, response to organic substance, response to organonitrogen compound, response to organic cyclic compound, negative regulation of translation, dentate gyrus development, central nervous system neuron development, neuron differentiation, neuron projection development, skeletal muscle cell differentiation, negative regulation of apoptotic process, response to peptide hormone, negative regulation of neuron apoptotic process, negative regulation of mitotic cell cycle, response to electrical stimulus, positive regulation of nuclear-transcribed mRNA poly(A) tail shortening, negative regulation of neural precursor cell proliferation. |
| BIOGRID_INTERACTION_ID | 113593 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 200130 200131 |
| MONOCLONAL_ANTIBODY | - |