Record No:1
| ACCESS NO | D109590 |
| GENE_NAME | H3F3B |
| DESCRIPTION | H3.3 histone B |
| ALIASES | H3-3A, H3.3B, H3-3B. |
| NCBI_ENTREZ_NO | 3021 |
| UNIPROT_ACCESS_NO | P84243 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Asthma, Allergic Rhinitis |
| SAMPLE | CD4 T cells |
| TECHNIQUES | RNA Sequencing |
| OMICS | Transcriptomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE75011 |
| COMMENTS | H3F3B was significantly decreased in asthmatics as compared to healthy subjects. |
| REFERENCE | 27271570 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | RNA polymerase II core promoter sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding, DNA binding, protein binding, nucleosomal DNA binding, protein heterodimerization activity. |
| GO_BIOLOGICAL_PROCESS | Chromatin silencing at rDNA, osteoblast differentiation, nucleosome assembly, DNA replication-independent nucleosome assembly, nucleus organization, spermatogenesis, spermatid development, single fertilization, brain development, embryo implantation, blood coagulation, cell proliferation, male gonad development, response to hormone, positive regulation of cell growth, pericentric heterochromatin assembly, telomeric heterochromatin assembly, telomere organization, multicellular organism growth, muscle cell differentiation, cellular protein metabolic process, regulation of megakaryocyte differentiation, negative regulation of gene expression (epigenetic), oogenesis, regulation of gene silencing by miRNA, regulation of centromere complex assembly, negative regulation of chromosome condensation. |
| BIOGRID_INTERACTION_ID | 109273 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 207657 207658 207659 207660 207661 207662 207663 207664 207665 207666 207667 207668 207669 207670 207671 207672 207673 207674 207675 |
| MONOCLONAL_ANTIBODY | Anti-Histone H3.3 antibody for Human, Mouse, Rat; Anti-Histone H3.3 (phospho S31) antibody for Human, Mouse, Rat; Anti-Histone H3.3 (mutated G34 V) antibody for Human; Anti-Histone H3.3 (mutated G34 W) antibody for Human; Anti-Histone H3.3 (mutated G34 R) antibody for Human. |